You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Take advantage of Flurry by weaving in basic attacks between spell casts - this maximizes damage output and minimizes Energy loss.
Self-casting Safeguard and using Iron Will are powerful tools for killing neutral monsters (in the jungle).
Use Sonic Wave before Dragon's Rage so you can chase the target with Resonating Strike.
The Neeko Lee Sin synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Lee Sin, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Lee Sin. His KDA fell from NaN to NaN. This fall shows that Lee Sin helps Neeko perform not as well in ranked League games. Yet, the small difference indicates that this performance change is only marginal.
When Neeko plays on the same team as Lee Sin, she gets a little decrease in her full damage dealt. This difference may indicate that Lee Sin does not provide cover for her to dish out more damage or that his allyship also helps increase the round's duration. Similarly, when Neeko is played together with Lee Sin on the same team, he usually scores many fewer killing sprees than when she plays without Lee Sin. This is contrasting evidence that she is worse when playing with Lee Sin.
Moreover, when Neeko plays with Lee Sin on the same team, she typically receives a little less damage than when she plays alone. Getting dealt not as much damage may indicate that Lee Sin does a decent job of protecting Neeko in teamfights.
There is no universally accepted best companion for Neeko that will no matter what be her best ally. However, Lee Sin is a below average teammate for Neeko. By locking into the same team as Neeko, he lowers their win rate by -1.1% to 48.3%. This shows that there is a bad bond between Neeko and Lee Sin that results in them performing not as well together than alone.
Lee Sin has a greater difficulty than Neeko. That means Neeko players need to be very careful when lining up Lee Sin comrades to go into battle on the same side as, as they will need a greater level of skill to be able to fight well with you.
Working together, you should expect to see an overall large increase in your team’s capability to deal magic damage. When paired, these champs can deal quite a lot of AP type damage.
Although, by grouping Neeko and Lee Sin together, you will not be granting your other teammates a lot of protection for burst damage. Plan to have other champions on your team that helps cover this relative hole in their kit.
Regardless of your Lee Sin ally's skill level, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you follow these simple suggestions, you will do well, regardless.
If you would like to learn all of the intricacies of Neeko in order to pair well with Lee Sin during both the early game and mid / late game phases of LoL, you should continue reading to master some more tricks and insights into this champion pairing. If you use the build and suggestions presented above, you will increase your win rate significantly.
The ideal finished items to get in your Neeko and Lee Sin synergy build consist of Rabadon's Deathcap, Hextech Rocketbelt, and Stormsurge. When Neeko combined at least these three finished items in her build, she did a lot better as an ally of Lee Sin than with many other common item sets. In fact, Neeko boasted an average win rate of 48.3% when synergizing her build and playstyle to Lee Sin with this build.
To have the highest chance of vanquishing your oponents, you should use the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune combinations players chose for this team composition, this composite of runes yielded the highest win rate. Moreover, these runes gave a 48.3% winrate overall.
By default, tips, stats, and builds on how to team up Lee Sin with Neeko are shown for every ranked division. If you would like to narrow the statistics and builds to a specific skill level, you can use the selection menu earlier in the counter matchup guide.