Miss Fortune ramps up speed if she hasn't recently taken damage. Avoid getting hit to move very fast.
Use Double Up on the furthest enemy minion if enemy champions are hiding in back; it will bounce to them for lots of damage.
Make sure to utilize Love Tap while Strut is on cooldown to maximize the active's availability.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Miss Fortune Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Miss Fortune sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA went down from NaN to NaN. This decrease shows that Karthus helps Miss Fortune perform worse in competitive League matches. Yet, the small difference proves that this performance change is only marginal.
When Miss Fortune is paired with Karthus, she observes a small increase in her full damage dealt. This change may indicate that Karthus provides cover for her to deal more damage or that his presence also helps extend the match's duration. Similarly, when Miss Fortune is played together with Karthus on the same team, he usually scores many fewer killing sprees than when she plays on his own. This is contrasting evidence that she is worse when playing with Karthus.
Additionally, when Miss Fortune plays with Karthus on the same team, she on average receives more damage than when she plays alone. Receiving more damage may indicate that Karthus does a poor job of covering Miss Fortune in team fights.
There is no one best ally for Miss Fortune that will no matter what be her top synergy. However, Karthus is a below average ally for Miss Fortune. By locking into the same side as Miss Fortune, he lowers their win rate by -2.8% to 50.6%. This signals that there is a harmful synergy between Miss Fortune and Karthus that allows them to perform worse together than alone.
Karthus has a much greater difficulty compared to Miss Fortune. That means Miss Fortune players need to be very careful when finding Karthus allies to fight alongside, as they will need a much higher level of skill to play well with you.
Fighting cooperatively, Miss Fortune players will likely see an overall large increase in your team’s ability to deal magical damage. Combined, these champions can blast through enemies with magic damage.
Conversely, by pairing Miss Fortune and Karthus together, you probably will not be giving your side a lot of tankyness. Make sure to include other champs on your team that fills this relative gap in their playstyle.
Regardless of your Karthus ally's skill level, you need to focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Miss Fortune in order to pair well with Karthus during both the lane and mid / late game phases of League games, you should continue reading to master some more tricks and insights into this champion pairing. If you use the build and suggestions displayed here, you should increase your win rate significantly.
The most crucial items to prioritize in your Miss Fortune and Karthus synergy build include The Collector, Serylda's Grudge, and Voltaic Cyclosword. When Miss Fortune combined at least these three items in her build, she did significantly better as an ally of Karthus than with most other commonly used item sets. In fact, Miss Fortune boasted an average win rate of 50.6% helping carry Karthus with this build.
To have the highest probability of defeating your oponents, you should take the First Strike, Magical Footwear, Biscuit Delivery, Cosmic Insight, Absolute Focus, and Gathering Storm runes from the Inspiration and Sorcery rune sets. Out of all the rune builds players picked for this champion pairing, this sequence of runes resulted in the greatest win rate. Notably, these runes gave a 50.6% win rate overall.
If you need to get Miss Fortune with Karthus synergy tips and builds for a a distinct skill level, feel free to choose one from the selection menu provided above. At first, the stats and guides displayed are calculated using all rounds finished with these champs.