Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Lillia Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Lillia sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA decreased from NaN to NaN. This negative change shows that Karthus helps Lillia perform not as well in competitive LoL matches. Yet, the small difference proves that this performance change is not very impactful.
When Lillia is paired with Karthus, she sees a little drop in her full damage dealt. This difference could indicate that Karthus does not provide protection for her to deal more damage or that his presence on the team also helps increase the match's duration. Similarly, when Lillia is played with Karthus on the same side, he usually scores many fewer killing sprees compared to when she plays without Karthus. This is contrasting evidence that she is worse when playing alongside Karthus.
Additionally, when Lillia plays with Karthus on the same side, she typically takes a little more damage than when she fights alone. Taking more damage may indicate that Karthus does a poor job of covering Lillia during teamfights.
There is no universally accepted best companion for Lillia that will 100% of the time be her #1 ally. Yet, Karthus is a terrible ally for Lillia. By locking into the same side as Lillia, he drops their win rate by -4.1% to 50.0%. This proves that there is a very bad bond between Lillia and Karthus that results in them performing not as well together than alone.
Karthus has a lower difficulty than Lillia. That means you don't need to be cautious when lining up Karthus allies to go into battle on the same side as, as they will need a relatively low level of skill to be able to fight well with you.
Playing cooperatively, you will likely observe an overall large increase in your team’s capability to deal magical damage. Together, these two can blast through enemies with magic damage.
In contrast, by aligning Lillia and Karthus together, you will not be granting your team very much anti-tank damage dealing potential. We recommend you bring other champions on your team that neutralizes this disparity in their kit.
Regardless of the ability of your Karthus ally, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Lillia in order to work well with Karthus during both the lane and mid / late game phases of League rounds, you should continue reading to learn additional lessons on this champion pairing. If you use the build and stats displayed here, you will increase your win rate by a lot.
The most important items to prioritize in your Lillia and Karthus synergy build include Rylai's Crystal Scepter, Riftmaker, and Liandry's Torment. When Lillia used at least these three great items in her build, she performed a lot better when paired up with Karthus than with most other typical item sets. In fact, Lillia had an average winrate of 50.0% helping carry Karthus with this build.
To have the highest chance of defeating your oponents, you should use the Conqueror, Triumph, Legend: Tenacity, Coup de Grace, Celerity, and Waterwalking runes from the Precision and Sorcery rune sets. Out of all the rune builds that we analyzed for this team composition, this mixture of runes yielded the best win rate. Moreover, these runes averaged a 50.0% win rate overall.
If you want to see Lillia and Karthus collaboration tips and stats for a a specific skill level, feel free to select one from the selection menu displayed above. By default, the statistics and tips and suggestions given are calculated using all matches run with these champions.