Take advantage of Flurry by weaving in basic attacks between spell casts - this maximizes damage output and minimizes Energy loss.
Self-casting Safeguard and using Iron Will are powerful tools for killing neutral monsters (in the jungle).
Use Sonic Wave before Dragon's Rage so you can chase the target with Resonating Strike.
You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
The Lee Sin Neeko synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Neeko, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Lee Sin sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Neeko. His KDA went down from NaN to NaN. This worsening shows that Neeko helps Lee Sin perform not as well in ranked League matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Lee Sin plays on the same team as Neeko, he gets a little decrease in his complete damage dealt. This may indicate that Neeko does not provide cover for him to dish out more damage or that her participation also helps increase the game's duration. Similarly, when Lee Sin is played alongside Neeko on the same team, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing alongside Neeko.
Additionally, when Lee Sin plays with Neeko on the same side, he typically receives a little more damage than when he plays alone. Receiving more damage may mean that Neeko does a poor job of covering Lee Sin in team fights.
There is no top synergy for Lee Sin that will 100% of the time be his #1 teammate. However, Neeko is a pretty good companion for Lee Sin. By playing on the same side as Lee Sin, she increases their win rate by 1.0% to 48.3%. This proves that there is a potentially meaningful strategic relationship between Lee Sin and Neeko that allows them to perform at the top of their game together than alone.
Neeko has a lower difficulty than Lee Sin. That means Lee Sin players don't need to be cautious when arranging Neeko comrades to fight alongside, as they will need a relatively low level of skill to be able to play well with you.
Playing together, Lee Sin players should expect to observe an overall large increase in your team’s capability to deal magic damage. When paired, these two can blast through enemies with magic damage.
In contrast, by bringing Lee Sin and Neeko together, you will not be giving your other teammates a lot of protection for burst damage. Make sure to bring other champions on your team that neutralizes this relative hole in their capabilities.
Regardless of your Neeko ally's ability, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you should do well anyway.
To truly master Lee Sin in order to work well with Neeko during both the laning and mid / late game phases of League of Legends rounds, you should keep reading to pick up a few extra tips and tricks for this champion pairing. If you use the build and tips displayed above, you should increase your win rate by a lot.
The top items to include in your Lee Sin and Neeko synergy build consist of Guardian Angel, Black Cleaver, and Sundered Sky. When Lee Sin bought at least these three items in his build, he performed much better when fighting alongside Neeko than with many other commonly used builds. In fact, Lee Sin boasted an average win rate of 48.3% when synergizing his build and playstyle to Neeko with these items in his kit.
To have the best likelihood of vanquishing your oponents, you should equip the Conqueror, Triumph, Legend: Alacrity, Coup de Grace, Cosmic Insight, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the rune builds players picked for this champion pairing, this sequence of runes yielded the greatest win rate. In fact, these runes gave a 48.3% win rate overall.
By default, tips, stats, and builds on how to synergize Neeko with Lee Sin are presented for all skill levels combined. To narrow the statistics and builds to a particular division, you can use the selection menu earlier in the counter matchup guide.