Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
Seeds grant vision to your team.
Placing a seed in your spell's path after you have cast it gives you the best chance of having a seed in the proper spot.
Zyra is a great ambusher - look for opportunities to set a trap of seeds in brush, then lure enemies in.
The Kassadin Zyra synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Zyra, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Kassadin sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Zyra. His KDA fell from NaN to NaN. This drop shows that Zyra helps Kassadin perform not as well in competitive LoL matches. Yet, the small difference proves that this performance change is not very impactful.
When Kassadin is an ally to Zyra, he sees a small increase in his complete damage dealt. This difference may indicate that Zyra helps provide protection for him to deal more damage or that her support also helps extend the round's duration. Similarly, when Kassadin is played together with Zyra on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing alongside Zyra.
Additionally, when Kassadin plays with Zyra on the same side, he often takes a little more damage than when he plays alone. Taking more damage may mean that Zyra does a poor job of protecting Kassadin in team fights.
There is no one best ally for Kassadin that will always be his #1 synergy. Yet, Zyra is a superb teammate for Kassadin. By being on the same team as Kassadin, she improves their win rate by 3.4% to 53.4%. This clearly indicates that there is a strong synergy between Kassadin and Zyra that results in them performing better together than alone.
Zyra has a lower difficulty than Kassadin. That means you don't need to be careful when arranging Zyra comrades to go into battle on the same side as, as they will have to have a relatively low level of skill to be able to cooperate well with you.
Playing cooperatively, Kassadin players should expect to observe an overall large increase in your team’s capacity to deal magic damage. Combined, these two are able to dish out a surprising amount of magic type damage.
Although, by grouping Kassadin and Zyra together, you may not be granting your team enough attack damage. Make sure to include other champions on your team that fills this disparity in this pairing's potential.
Regardless of the ability of your Zyra ally, you need to focus on maximizing your income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
If you would like to truly master Kassadin in order to pair well with Zyra during both the lane and mid / late game phases of LoL games, you should continue reading to gather additional tips and tricks for this champion pairing. If you mind the build and stats displayed above, you should grow your win rate by a lot.
The ideal items to have in your Kassadin and Zyra synergy build include Rabadon's Deathcap, Malignance, and Rod of Ages. When Kassadin included at least these three great items in his build, he performed much better as an ally of Zyra than with most other commonly used item sets. In fact, Kassadin boasted an average winrate of 53.4% when playing alongside Zyra with this build.
To have the greatest chance of beating your oponents, you should equip the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Sudden Impact, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune builds players used for this team composition, this sequence of runes yielded the greatest win rate. Notably, these runes gave a 53.4% win rate overall.
If you need to get Kassadin and Zyra synergy tips and builds for a a particular player tier, feel free to choose one from the selection menu displayed above. If viewing for the first time, the statistics and tips and suggestions given are computed using all rounds played with these champions.