Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
The Kassadin Zilean synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Zilean, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Kassadin sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Zilean. His KDA decreased from NaN to NaN. This fall shows that Zilean helps Kassadin perform not as well in ranked League of Legends games. Yet, the small difference proves that this performance change is only marginal.
When Kassadin plays on the same team as Zilean, he observes a sizeable uptick in his full damage output. This change could demonstrate that Zilean provides cover for him to deal more damage or that his allyship also helps increase the game's duration. Similarly, when Kassadin is played with Zilean on the same team, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing alongside Zilean.
Moreover, when Kassadin plays with Zilean on the same side, he usually takes more damage than when he plays alone. Receiving more damage could indicate that Zilean does a poor job of covering Kassadin during teamfights.
There is no perfect companion for Kassadin that will no matter what be his best ally. However, Zilean is a good teammate for Kassadin. By playing on the same side as Kassadin, he increases their win rate by 2.1% to 52.1%. This shows that there is pretty good bond between Kassadin and Zilean that results in them performing at the top of their game together than alone.
Zilean has a lower difficulty than Kassadin. That means you don't need to be very careful when enlisting Zilean allies to play with, as they will have to have a relatively low level of skill to cooperate well with you.
When playing cooperatively, Kassadin players should expect to observe an overall large increase in your team’s capability to deal magic damage. When paired, these champions can blast through enemies with magic damage.
In contrast, by bringing Kassadin and Zilean together, you may not be providing your other allies a lot of sustained damage output. We recommend you have other champions on your team that offsets this gap in this pairing's playstyle.
Regardless of the skill of your Zilean ally, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you should do well, regardless.
To truly master Kassadin in order to pair well with Zilean during both the lane and mid / late game phases of LoL games, you should continue reading to master additional tips and tricks for this champion pairing. If you pay attention to the build and tips shown above, you will grow your win rate by a lot.
The best finished items to build first in your Kassadin and Zilean synergy build consist of Seraph's Embrace, Rabadon's Deathcap, and Malignance. When Kassadin included at least these three pieces in his build, he did much better when fighting alongside Zilean than with most other typical item sets. In fact, Kassadin had an average winrate of 52.1% when playing alongside Zilean with these items in his kit.
To have the best chance of defeating your oponents, you should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Sudden Impact, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the runes that we analyzed for this champion pairing, this set of runes resulted in the best win rate. In fact, these runes gave a 52.1% winrate overall.
By default, tips, stats, and builds on how to synergize Zilean with Kassadin are shown for all skill levels combined. To narrow the statistics and builds to a specific division, you can use the selection menu earlier in the counter matchup guide.