Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
Lissandra's abilities are shorter range than those of many mages. As a result, buying items that offer both ability power and defense, like Zhonya's Hourglass and Banshee's Veil, can be a great choice to help her both survive and deal damage.
Casting Glacial Path and then running in the opposite direction will leave your enemies uncertain which way you will actually go.
You can instantly use your ultimate on yourself by pressing the self cast key and the ultimate key at once (alt+R by default).
The Kassadin Lissandra synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Lissandra, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Kassadin sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Lissandra. His KDA worsened from NaN to NaN. This fall shows that Lissandra helps Kassadin perform poorer in competitive League of Legends matches. Yet, the small difference proves that this performance change is not very impactful.
When Kassadin tries to synergize with Lissandra, he gets a little decrease in his complete damage dealt. This difference may demonstrate that Lissandra does not support by providing protection for him to deal more damage or that her presence on the team also helps extend the match's duration. Similarly, when Kassadin is played with Lissandra on the same team, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing alongside Lissandra.
Additionally, when Kassadin plays with Lissandra on the same side, he often receives a little more damage than when he fights alone. Receiving more damage may indicate that Lissandra does a poor job of covering Kassadin during team fights.
There is no top ally for Kassadin that will always be his ideal synergy. However, overall, Lissandra is a very bad companion for Kassadin. By being on the same team as Kassadin, she lowers their win rate by -4.0% to 46.0%. This shows that there is a very bad synergy between Kassadin and Lissandra that results in them performing not as well together than alone.
Lissandra has a lower difficulty than Kassadin. That means you don't need to be careful when finding Lissandra allies to fight alongside, as they will require a lower level of skill to be able to fight well with you.
Working together, you will likely witness an overall large increase in your team’s ability to to do a lot of AP damage. Together, these two are able to dish out a surprising amount of magic type damage.
Although, by grouping Kassadin and Lissandra together, you probably will not be granting your other teammates enough AD. Plan to bring other champions on your team that offsets this relative gap in this pairing's playstyle.
Regardless of the ability of your Lissandra teammate, you should focus on maximizing your income, outlasting your enemies, and clearing objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Kassadin to synergize with Lissandra during both the laning and mid / late game phases of LoL matches, you should keep reading to gather some more tips and tricks for this champion pairing. If you listen to the build and suggestions displayed above, you will grow your win rate by a lot.
The best finished items to get in your Kassadin and Lissandra synergy build include Seraph's Embrace, Lich Bane, and Malignance. When Kassadin used at least these three great items in his build, he did significantly better when paired up with Lissandra than with many other common builds. In fact, Kassadin boasted an average winrate of 46.0% when playing alongside Lissandra with these items in his kit.
To have the highest probability of defeating your oponents, you should equip the Electrocute, Sudden Impact, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Legend: Tenacity runes from the Domination and Precision rune sets. Of all the runes players chose for Kassadin and Lissandra pairings, this combination of runes yielded the top win rate. In fact, these runes averaged a 46.0% winrate overall.
By default, tips, stats, and builds on how to team up Lissandra with Kassadin are displayed for all ranked divisions combined. To scope the statistics and builds to a specific rank, you can use the selection menu earlier in the counter matchup guide.