Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
Use Arcane Shift to help line up your other skill shots.
You can line up Trueshot Barrage to hit multiple minion waves or even Monsters.
You can play Ezreal either as a Attack Damage carry or Ability Power carry depending on how you build him.
The Kassadin Ezreal synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Ezreal, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Kassadin sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Ezreal. His KDA fell from NaN to NaN. This negative change shows that Ezreal helps Kassadin perform not as well in ranked League rounds. Yet, the small difference proves that this performance change is not very impactful.
When Kassadin plays on the same team as Ezreal, he observes a small decrease in his complete damage dealt. This may indicate that Ezreal does not help cover for him to dish out more damage or that his allyship also helps extend the round's duration. Similarly, when Kassadin is played together with Ezreal on the same side, he usually scores many fewer killing sprees compared to when he plays without Ezreal. This is contrasting evidence that he is worse when playing synergisticly with Ezreal.
Moreover, when Kassadin plays with Ezreal on the same side, he typically receives a little more damage than when he plays alone. Getting dealt more damage could mean that Ezreal does a poor job of covering Kassadin in team fights.
There is no perfect synergy for Kassadin that will no matter what be his ideal ally. However, Ezreal is a below average ally for Kassadin. By playing on the same team as Kassadin, he drops their win rate by -2.0% to 48.0%. This signals that there is a negative strategic relationship between Kassadin and Ezreal that results in them performing not as well together than without each other.
Ezreal has a lower difficulty than Kassadin. That means you don't need to be careful when finding Ezreal comrades to play with, as they will require a lower level of skill to be able to fight well with you.
Fighting alongside, Kassadin players should expect to observe an overall large increase in your team’s capability to deal magical damage. Combined, these champions can deal quite a lot of AP type damage.
In contrast, by bringing Kassadin and Ezreal together, you may not be providing your other allies much utility. Make sure to bring other champions on your team that neutralizes this relative gap in this pairing's capabilities.
Regardless of your Ezreal ally's ability, you should focus on increasing your gold income, warding to avoid ambushes, and taking down objectives. If you do this, you will do well, regardless.
To truly master Kassadin in order to pair well with Ezreal during both the laning and mid / late game phases of League of Legends, you should keep reading to gather a few extra tips and tricks for this champion pairing. If you use the build and suggestions displayed above, you will grow your win rate by a lot.
The ideal finished items to include in your Kassadin and Ezreal synergy build include Rabadon's Deathcap, Malignance, and Rod of Ages. When Kassadin included at least these three finished items in his build, he did a lot better when paired up with Ezreal than with many other typical builds. In fact, Kassadin boasted an average win rate of 48.0% when synergizing his build and playstyle to Ezreal with these items in his kit.
To have the highest likelihood of coming out on top against your oponents, you should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Sudden Impact, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the runes players picked for Kassadin and Ezreal pairings, this sequence of runes resulted in the highest win rate. Notably, these runes gave a 48.0% win rate overall.
By default, tips, statistics, and builds on how to pair Ezreal with Kassadin are given for all skill levels combined. To narrow the statistics and builds to a specific rank, you can use the selection menu located earlier on the page.