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How to Synergize Karthus with Zoe on the Same TeamKarthus is in the b tier of champions

Karthus with Zoe

How to Win With Karthus and Zoe Paired TogetherKarthus is in the b tier of champions
Mage
MageSupport

How to Synergize Karthus and Zoe

based on 422 Karthus with Zoe pairs
Win Rate
46.4 %
K/D/A
2.09
Pick Rate
0.9 %

How We Analyze Champion Pairings in LoL

We download the results of from millions of LoL rounds straight from Riot Games each week. Karthus has been on the same team as Zoe in 422 recently played, competitive matches. By gathering so much complete data from the makers of League of Legends, we feel confident that we can give you robust, usable builds to help Karthus synergize with Zoe. It is very rare for Karthus to play alongside Zoe as allies. This has only taken place in about 0.9% of games with Karthus.

Karthus Zoe Synergy Summary

Unfortunately, Karthus has done a terrible job of teaming up with Zoe. Typically, he wins a dismal 46.4% of rounds the champs play on the same team. If you want to play better as Karthus when fighting on the same team as Zoe by figuring out how to better synergize your playstyle with her, then look into the full build (with items, runes, summoner spells, and skills) below!

Best Karthus vs Zoe Counter Build

Items

Starter Items

Time Target
Scorchclaw PupHealth Potion

Early Items

~5 Mins
Amplifying TomeLost Chapter

Core Karthus Items

~22 Mins
Rabadon's DeathcapMalignanceShadowflame

Optional Items

Liandry's TormentStormsurge

Summoner Spells

summonerexhaust summoner spell D
summonersmite summoner spell F

Skill Order

First skill for Karthus to level upq
>
Second ability for Karthus to level upe
>
Last skill for Karthus to max outw

Runes

DominationDark HarvestCheap ShotEyeball CollectionUltimate Hunter
SorceryTranscendenceGathering Storm
Adaptive ForceAdaptive ForceArmor
Karthus's passive ability p
Karthus's q ability q
Karthus's w ability w
Karthus's e ability e
Karthus's ultimate ability r
1
Q
2
E
3
W
4
Q
5
Q
6
R
7
Q
8
E
9
Q
10
E
11
R
12
E
13
E
14
W
15
W
16
R

Guide to Synergizing Karthus and Zoe

Tips for Playing as Karthus with Zoe

Lay Waste is very strong at farming minions and harassing enemy champions.

Ask your allies to help point out when you should use Requiem to get kills in different lanes.

Advice to Understand How Zoe Will Play

Sleepy Trouble Bubble travels further over walls. Find a hiding spot to set up for a long distance kill.

Break Sleep with your biggest damage source, since enemies who are asleep take double damage.

Paddle Star deals more damage the further it has flown. Casting it behind yourself before redirecting can deal tons of damage.

Karthus Zoe Synergy Stats

Karthus Image
Win Rate
46.4 %
VS
Win Rate
53.6 %
Zoe Image
6.9
< Kills >
7
7.7
< Deaths >
7.6
9.2
< Assists >
9.5
1.61
< Killing Sprees >
1.63
81
< Minions Killed >
88
0.95
< Dragons Killed >
0.89
0.3
< Inhibitors >
0.28
242
< Physical Damage >
246
28,933
< Magic Damage >
29,153
2,106
< True Damage >
2,031
31,282
< Damage Dealt >
31,430
31,007
< Damage Taken >
29,785
12,844
< Gold Earned >
12,799
1.11
< Towers >
1.08
0.23
< Baron Takedowns >
0.23
10,209
< Total Healing >
9,279
15,003
< Experience >
14,921
20
< Vision Score >
19
7
< Wards Placed >
7
224
< Time Dealing CC >
221

How to Play with Zoe as Karthus in LoL

The Karthus Zoe synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Zoe, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.

Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Zoe. His KDA decreased from NaN to NaN. This decrease shows that Zoe helps Karthus perform not as well in competitive League of Legends games. Yet, the small difference proves that this performance change is not very impactful.

When Karthus is an ally to Zoe, he gets a little drop in his total damage output. This could signal that Zoe doesn't help protection for him to dish out more damage or that her participation also helps extend the round's duration. Similarly, when Karthus is played alongside Zoe on the same team, he usually scores many fewer killing sprees compared to when he plays on his own. This is contrasting evidence that he is worse when playing synergisticly with Zoe.

Additionally, when Karthus plays with Zoe on the same team, he usually takes a little more damage than when he plays alone. Taking more damage may indicate that Zoe does a poor job of protecting Karthus in teamfights.

Synergies between Karthus and Zoe

Damage Types Compared

Karthus
Zoe
Physical Damage
Magic Damage
True Damage

Champion Playstyles Contrasted

Karthus
Zoe

Is Karthus better when played alongside Zoe?

There is no top synergy for Karthus that will no matter what be his top synergy. Yet, Zoe is a very typical ally for Karthus. By locking into the same side as Karthus, she decreases their win rate by -0.9% to 46.4%. This demonstrates that there is only a small bond between Karthus and Zoe that allows them to perform not as well together than without each other.

Zoe has a lower difficulty than Karthus. That means you don't need to be careful when enlisting Zoe allies to go into battle on the same side as, as they will require a relatively low level of skill to do well with you.

Fighting on the same side, you will likely see an overall large increase in your team’s capacity to deal magical damage. When paired, these champions can deal quite a lot of AP type damage.

Although, by pairing Karthus and Zoe together, you may not be giving your other allies a great deal of anti-tank damage dealing potential. Make sure to include other champions on your team that helps cover this relative gap in this pairing's kit.

Regardless of the skill of your Zoe ally, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you should do well anyway.

Additional Information for Karthus Players

How We Calculated Our Karthus Zoe Synergy Build and Stats

For this guide on pairing Karthus and Zoe, we analyzed 422 ranked and recent League of Legends matches. We perform advanced data cleaning and statistical methods to guarantee that our team synergy stats are accurate and reliable. You can be confident that our recommended build to pair Karthus with Zoe comes from actual data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view your division's most relevant stats and build.

Other Useful Resources

Further Insights to Win with this Champion Pairing

If you would like to learn all of the intricacies of Karthus in order to pair well with Zoe during both the lane and mid / late game phases of LoL matches, you should continue reading to pick up a few extra tips and tricks for this champion pairing. If you listen to the build and suggestions shown above, you will increase your win rate by a lot.

The most important items to prioritize in your Karthus and Zoe synergy build include Rabadon's Deathcap, Malignance, and Shadowflame. When Karthus included at least these three finished items in his build, he did significantly better when paired up with Zoe than with many other commonly used item sets. In fact, Karthus had an average winrate of 46.4% helping carry Zoe with these items in his kit.

To have the highest likelihood of defeating your oponents, you should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the runes we have analyed for Karthus and Zoe pairings, this set of runes yielded the top win rate. Moreover, these runes gave a 46.4% winrate overall.

By default, tips, stats, and builds on how to team up Zoe with Karthus are displayed for all ranked divisions combined. To filter the stats and builds to a specific rank, you should use the selection menu located at the top of this page.