Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Karthus Zeri synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Zeri, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Zeri. His KDA decreased from NaN to NaN. This worsening shows that Zeri helps Karthus perform poorer in ranked League of Legends rounds. Yet, the small difference indicates that this performance change is only marginal.
When Karthus is paired with Zeri, he gets a barely noticable drop in his complete damage output. This may signal that Zeri does not help protection for him to deal more damage or that their presence on the team also helps extend the round's duration. Similarly, when Karthus is played together with Zeri on the same team, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing with Zeri.
Moreover, when Karthus plays with Zeri on the same team, he typically receives a little more damage than when he plays alone. Getting dealt more damage could indicate that Zeri does a poor job of covering Karthus in teamfights.
There is no perfect companion for Karthus that will always be his #1 teammate. Yet, overall, Zeri is a terrible companion for Karthus. By locking into the same side as Karthus, they lowers their win rate by -3.3% to 44.0%. This proves that there is a very bad bond between Karthus and Zeri that results in them performing worse together than alone.
Zeri has a lower difficulty than Karthus. That means Karthus players don't need to be careful when enlisting Zeri comrades to play with, as they will require a relatively low level of skill to be able to cooperate well with you.
Working alongside, Karthus players should see an overall large increase in your team’s ability to deal magical damage. Together, these champions are able to dish out a surprising amount of magic type damage.
In contrast, by aligning Karthus and Zeri together, you may not be granting your team much tankyness. We recommend you include other champions on your team that neutralizes this hole in this pairing's kit.
Regardless of the ability of your Zeri teammate, you should focus on increasing your gold income, warding to avoid ambushes, and taking down objectives. If you follow these simple suggestions, you will do well anyway.
To truly master Karthus to work well with Zeri during both the laning and mid / late game phases of League of Legends rounds, you should continue reading to learn a few extra lessons on this champion pairing. If you mind the build and suggestions displayed above, you should increase your win rate by a lot.
The most important finished items to build first in your Karthus and Zeri synergy build include Rabadon's Deathcap, Malignance, and Liandry's Torment. When Karthus used at least these three pieces in his build, he did a lot better as an ally of Zeri than with many other common item sets. In fact, Karthus boasted an average win rate of 44.0% when playing alongside Zeri with these items in his kit.
To have the greatest chance of beating your oponents, you should equip the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the runes players picked for this champion pairing, this mix of runes yielded the best win rate. Notably, these runes gave a 44.0% win rate overall.
If you need to get Karthus with Zeri synergy tips and builds for a a specific skill level, please select one from the selection menu provided above. At first, the statistics and guides displayed are calculated using all matches with data with these champions.