Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
The Karthus Vladimir synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vladimir, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Vladimir. His KDA decreased from NaN to NaN. This decrease shows that Vladimir helps Karthus perform not as well in ranked League of Legends rounds. Yet, the small difference shows that this performance change is only marginal.
When Karthus is paired with Vladimir, he sees a little decrease in his full damage dealt. This could demonstrate that Vladimir does not support by providing cover for him to deal more damage or that his presence also helps extend the round's duration. Similarly, when Karthus is played alongside Vladimir on the same team, he usually scores many fewer killing sprees compared to when he plays on his own. This is contrasting evidence that he is worse when playing with Vladimir.
Moreover, when Karthus plays with Vladimir on the same side, he on average receives a little more damage than when he plays alone. Taking more damage could indicate that Vladimir does a poor job of protecting Karthus in team fights.
There is no one best ally for Karthus that will 100% of the time be his #1 teammate. However, overall, Vladimir is a very typical ally for Karthus. By playing on the same side as Karthus, he drops their win rate by -0.2% to 47.1%. This demonstrates that there is only a small strategic relationship between Karthus and Vladimir that results in them performing not as well together than alone.
Vladimir has a lower difficulty than Karthus. That means you don't need to be cautious when finding Vladimir teammates to go into battle on the same side as, as they will need a lower level of skill to play well with you.
Playing on the same side, Karthus players should expect to observe an overall large increase in your team’s capacity to deal magical damage. Together, these two can blast through enemies with magic damage.
Although, by grouping Karthus and Vladimir together, you will not be granting your other allies a great deal of sustained damage output. Plan to include other champions on your team that fills this relative hole in their kit.
Regardless of the ability of your Vladimir ally, you need to focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you should do well anyway.
If you would like to learn all of the intricacies of Karthus to synergize with Vladimir during both the lane and mid / late game phases of LoL matches, you should continue reading to master additional tips and tricks for this champion pairing. If you mind the build and tips presented here, you will grow your win rate significantly.
The best finished items to use in your Karthus and Vladimir synergy build include Malignance, Stormsurge, and Liandry's Torment. When Karthus combined at least these three pieces in his build, he did a lot better when fighting alongside Vladimir than with most other common builds. In fact, Karthus boasted an average win rate of 47.1% when synergizing his build and playstyle to Vladimir with these items in his kit.
To have the greatest probability of coming out on top against your oponents, you should use the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Out of all the rune sets players picked for this champion pairing, this sequence of runes resulted in the highest win rate. Notably, these runes averaged a 47.1% win rate overall.
By default, tips, stats, and builds on how to pair Vladimir with Karthus are given for every ranked division. If you want to narrow the stats and builds to a specific player tier, you should use the selection menu located at the top of this page.