Karthus with Vayne
How to Synergize Karthus and Vayne
based on 2,347 Karthus with Vayne pairsHow We Analyze Champion Pairings in LoL
Karthus Vayne Synergy Summary
Best Karthus vs Vayne Counter Build
Items
Starter Items
Early Items
Core Karthus Items
Optional Items
Summoner Spells
Skill Order
Runes
Guide to Synergizing Karthus and Vayne
Tips for Playing as Karthus with Vayne
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Advice to Understand How Vayne Will Play
Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Karthus Vayne Synergy Stats
How to Play with Vayne as Karthus in LoL
The Karthus Vayne synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vayne, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA went down from NaN to NaN. This worsening shows that Vayne helps Karthus perform poorer in ranked LoL games. Yet, the small difference demonstrates that this performance change is not very impactful.
When Karthus is an ally to Vayne, he gets a small decrease in his total damage dealt. This difference may signal that Vayne does not provide protection for him to deal more damage or that her presence also helps increase the match's duration. Similarly, when Karthus is played alongside Vayne on the same team, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing with Vayne.
Moreover, when Karthus plays with Vayne on the same team, he usually takes a little more damage than when he plays alone. Taking more damage could indicate that Vayne does a poor job of covering Karthus during teamfights.
Synergies between Karthus and Vayne
Damage Types Compared
Champion Playstyles Contrasted
Is Karthus better when played alongside Vayne?
There is no universally accepted best champion pairing for Karthus that will no matter what be his top ally. However, Vayne is a very typical teammate for Karthus. By locking into the same side as Karthus, she lowers their win rate by -0.9% to 46.4%. This proves that there is only a small strategic relationship between Karthus and Vayne that results in them performing not as well together than alone.
Vayne has a greater difficulty than Karthus. That means Karthus players should be careful when finding Vayne comrades to fight alongside, as they will have to have a greater level of skill to cooperate well with you.
When playing alongside, Karthus players should expect to see an overall large increase in your team’s capability to destroy wih physical damage. Together, these champions should be able to take down targets with auto-attacks and other AD damage abilities.
Although, by grouping Karthus and Vayne together, you probably will not be granting your team a lot of engage potential. We recommend you pick other champions on your team that neutralizes this hole in this pairing's playstyle.
Regardless of your Vayne ally's skill level, you should focus on increasing your gold income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you should do well, regardless.
Other Champion Matchups Against Karthus
Other Top Synergies by Role
Additional Information for Karthus Players
How We Calculated Our Karthus Vayne Synergy Build and Stats
Other Useful Resources
Further Insights to Win with this Champion Pairing
If you would like to learn all of the intricacies of Karthus in order to pair well with Vayne during both the lane and mid / late game phases of League of Legends games, you should continue reading to master additional tricks and insights into this champion pairing. If you listen to the build and suggestions shown above, you should grow your win rate significantly.
The top items to prioritize in your Karthus and Vayne synergy build consist of Rabadon's Deathcap, Stormsurge, and Liandry's Torment. When Karthus included at least these three items in his build, he did significantly better when fighting alongside Vayne than with many other common item sets. In fact, Karthus had an average winrate of 46.4% helping carry Vayne with this build.
To have the greatest chance of crushing your oponents, Karthus players should use the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune builds players used for this champion pairing, this combo of runes yielded the top win rate. Moreover, these runes provided a 46.4% winrate overall.
By default, tips, statistics, and builds on how to pair Vayne with Karthus are shown for all ranked divisions combined. To filter the statistics and builds to an individual skill level, you may use the selection menu located earlier on the page.