Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Delaying the activation of Undying Rage is a very effective way to make an enemy champion over-commit to trying to kill you.
If the enemy is stacking Armor, try building items like Last Whisper or Youmuu's Ghostblade.
Bloodlust is an excellent way to heal Tryndamere. Try not to let it fade off before you activate it.
The Karthus Tryndamere synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Tryndamere, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Tryndamere. His KDA went down from NaN to NaN. This worsening shows that Tryndamere helps Karthus perform not as well in competitive League games. Yet, the small difference demonstrates that this performance change is not very impactful.
When Karthus tries to synergize with Tryndamere, he gets a little drop in his total damage dealt. This may demonstrate that Tryndamere does not support by providing cover for him to dish out more damage or that his support also helps extend the match's duration. Similarly, when Karthus is played alongside Tryndamere on the same team, he usually scores many fewer killing sprees than when he plays without Tryndamere. This is contrasting evidence that he is worse when playing synergisticly with Tryndamere.
Additionally, when Karthus plays with Tryndamere on the same team, he usually receives a little less damage than when he plays alone. Receiving not as much damage may mean that Tryndamere does a decent job of protecting Karthus during team fights.
There is no one best companion for Karthus that will always be his best synergy. Yet, overall, Tryndamere is a decent teammate for Karthus. By locking into the same team as Karthus, he raises their win rate by 1.2% to 48.5%. This signals that there is a good strategic relationship between Karthus and Tryndamere that results in them performing stronger together than without each other.
Tryndamere has a lower difficulty than Karthus. That means Karthus players don't need to be cautious when lining up Tryndamere comrades to fight alongside, as they will require a relatively low level of skill to be able to do well with you.
Working on the same side, Karthus players should expect to witness an overall large increase in your team’s ability to dish out massive AD. Combined, these two can tear through the other team with a lot of physcial damage.
Although, by pairing Karthus and Tryndamere together, you may not be giving your team much crowd control. Plan to bring other champs on your team that offsets this relative disparity in their potential.
Regardless of the skill of your Tryndamere teammate, you should focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you heed this simple advice, you will do well anyway.
If you would like to truly master Karthus in order to pair well with Tryndamere during both the laning and mid / late game phases of League of Legends matches, you should keep reading to pick up some more tricks and insights into this champion pairing. If you mind the build and stats presented above, you will increase your win rate significantly.
The most important finished items to use in your Karthus and Tryndamere synergy build include Rabadon's Deathcap, Malignance, and Liandry's Torment. When Karthus included at least these three great items in his build, he performed significantly better when paired up with Tryndamere than with many other common builds. In fact, Karthus had an average winrate of 48.5% helping carry Tryndamere with this build.
To have the highest likelihood of annihilating your oponents, you should use the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune combinations that we analyzed for this champion pairing, this set of runes resulted in the top win rate. Notably, these runes averaged a 48.5% win rate overall.
If you need to get Karthus and Tryndamere cooperations tips and stats for a a particular player tier, feel free to choose one from the selection menu displayed above. At first, the statistics and build suggestions given are computed using all games with data with both champions.