Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
While laning, try to use Death's Hand's piercing damage to damage opponents from a safe distance.
Vision of Empire is quite difficult to land on its own, look for skirmishes around the map where enemies may be distracted or crowd controlled so you can land it more easily.
If you're having trouble rooting an enemy with Nevermove, try throwing it at opponents when they are near their minions so the explosion surprises them.
Demonic Ascension may make Swain very hard to kill but he's pretty easy to get away from. Try building items that can slow opponents to keep them in range if their mobility is overwhelming.
The Karthus Swain synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Swain, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Swain. His KDA fell from NaN to NaN. This worsening shows that Swain helps Karthus perform worse in ranked League of Legends rounds. Yet, the small difference shows that this performance change is only marginal.
When Karthus is an ally to Swain, he gets a small increase in his complete damage dealt. This difference could signal that Swain provides protection for him to deal more damage or that his presence also helps extend the game's duration. Similarly, when Karthus is played with Swain on the same side, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing with Swain.
Additionally, when Karthus plays with Swain on the same side, he usually takes a little more damage than when he plays alone. Taking more damage may indicate that Swain does a poor job of covering Karthus during team fights.
There is no universally accepted best companion for Karthus that will always be his ideal synergy. However, overall, Swain is a very typical teammate for Karthus. By locking into the same team as Karthus, he drops their win rate by -0.7% to 46.6%. This demonstrates that there is only a small synergy between Karthus and Swain that allows them to perform not as well together than without each other.
Swain has a greater difficulty than Karthus. That means you must be careful when arranging Swain teammates to go into battle on the same side as, as they will need a greater level of skill to be able to cooperate well with you.
Working cooperatively, Karthus players will likely witness an overall large increase in your team’s capability to to do a lot of AP damage. When paired, these champs can deal quite a lot of AP type damage.
Conversely, by aligning Karthus and Swain together, you will not be granting your other allies a lot of attack damage. Plan to have other champions on your team that helps cover this disparity in their playstyle.
Regardless of your Swain ally's ability, you need to focus on increasing your gold income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you will do well, regardless.
If you would like to learn all of the intricacies of Karthus in order to work well with Swain during both the lane and mid / late game phases of League rounds, you should continue reading to learn a few extra tips and tricks for this champion pairing. If you listen to the build and tips displayed above, you will grow your win rate by a lot.
The ideal items to include in your Karthus and Swain synergy build consist of Rabadon's Deathcap, Malignance, and Shadowflame. When Karthus bought at least these three finished items in his build, he performed a lot better when paired up with Swain than with most other typical builds. In fact, Karthus had an average winrate of 46.6% when playing alongside Swain with this build.
To have the highest chance of vanquishing your oponents, you should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune builds that we analyzed for this team composition, this mix of runes resulted in the top win rate. In fact, these runes provided a 46.6% winrate overall.
By default, tips, stats, and builds on how to pair Swain with Karthus are shown for every ranked division. To narrow the statistics and builds to a specific division, you can use the selection menu earlier in the counter matchup guide.