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How to Synergize Karthus with Senna on the Same TeamKarthus is in the b tier of champions

Karthus with Senna

How to Win With Karthus and Senna Paired TogetherKarthus is in the s tier of champions
Mage
MarksmanSupport

How to Synergize Karthus and Senna

based on 4,177 Karthus with Senna pairs
Win Rate
47 %
K/D/A
2.12
Pick Rate
8.6 %

How We Analyze Champion Pairings in LoL

At MOBA Champion, we take in data from from millions of LoL matches directly from Riot Games each and every week. Karthus has been on the same team as Senna in 4177 recently played, competitive matches. By gathering so much accurate data directly from the hosts of League, we feel confident that we can showcase high-quality, insightful builds to help Karthus synergize with Senna. It is common for Karthus to play alongside Senna as teammates. This pairing has happened in about 8.6% of games with Karthus.

Karthus Senna Synergy Summary

Unfortunately, Karthus has done a dismal job of synergizing with Senna. On average, he wins a poor 47.0% of the time the champs try and synergize their gameplay. If you want to play better as Karthus when fighting on the same team as Senna by learning how to better synergize your playstyle with her, then look into the full build (with items, runes, summoner spells, and skills) below!

Best Karthus vs Senna Counter Build

Items

Starter Items

Time Target
Doran's RingHealth Potion

Early Items

~5 Mins
Fiendish CodexLost Chapter

Core Karthus Items

~22 Mins
Void StaffShadowflameStormsurge

Optional Items

Rabadon's DeathcapZhonya's HourglassLiandry's TormentRylai's Crystal Scepter

Summoner Spells

summonerexhaust summoner spell D
summonerflash summoner spell F

Skill Order

First skill for Karthus to level upq
>
Second ability for Karthus to level upe
>
Last skill for Karthus to max outw

Runes

DominationDark HarvestCheap ShotEyeball CollectionUltimate Hunter
PrecisionPresence of MindLast Stand
Adaptive ForceAdaptive ForceHealth Scaling
Karthus's passive ability p
Karthus's q ability q
Karthus's w ability w
Karthus's e ability e
Karthus's ultimate ability r
1
Q
2
E
3
Q
4
W
5
Q
6
R
7
Q
8
E
9
Q
10
E
11
R
12
E
13
E
14
W
15
W
16
R

Guide to Synergizing Karthus and Senna

Tips for Playing as Karthus with Senna

Lay Waste is very strong at farming minions and harassing enemy champions.

Ask your allies to help point out when you should use Requiem to get kills in different lanes.

Karthus Senna Synergy Stats

Karthus Image
Win Rate
47 %
VS
Win Rate
53 %
Senna Image
6.8
< Kills >
7
7.6
< Deaths >
7.6
9.3
< Assists >
9.5
1.59
< Killing Sprees >
1.63
98
< Minions Killed >
88
0.79
< Dragons Killed >
0.89
0.27
< Inhibitors >
0.28
231
< Physical Damage >
246
28,617
< Magic Damage >
29,153
1,901
< True Damage >
2,031
30,749
< Damage Dealt >
31,430
29,542
< Damage Taken >
29,785
12,713
< Gold Earned >
12,799
1.11
< Towers >
1.08
0.21
< Baron Takedowns >
0.23
8,765
< Total Healing >
9,279
14,802
< Experience >
14,921
18
< Vision Score >
19
7
< Wards Placed >
7
215
< Time Dealing CC >
221

How to Play with Senna as Karthus in LoL

The Karthus Senna synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Senna, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.

Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Senna. His KDA decreased from NaN to NaN. This worsening shows that Senna helps Karthus perform not as well in competitive LoL games. Yet, the small difference demonstrates that this performance change is not very impactful.

When Karthus tries to synergize with Senna, he gets a little drop in his complete damage output. This could demonstrate that Senna doesn't help cover for him to dish out more damage or that her allyship also helps increase the game's duration. Similarly, when Karthus is played together with Senna on the same side, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing alongside Senna.

Additionally, when Karthus plays with Senna on the same side, he usually takes a little less damage than when he plays alone. Receiving not as much damage could indicate that Senna does a decent job of protecting Karthus in teamfights.

Synergies between Karthus and Senna

Damage Types Compared

Karthus
Senna
Physical Damage
Magic Damage
True Damage

Champion Playstyles Contrasted

Karthus
Senna

Is Karthus better when played alongside Senna?

There is no one best synergy for Karthus that will no matter what be his #1 ally. Yet, Senna is a very typical companion for Karthus. By locking into the same team as Karthus, she drops their win rate by -0.3% to 47.0%. This shows that there is not really a strong bond between Karthus and Senna that allows them to perform not as well together than without each other.

Senna has a lower difficulty than Karthus. That means Karthus players don't need to be cautious when enlisting Senna allies to fight alongside, as they will require a relatively low level of skill to be able to play well with you.

Fighting cooperatively, Karthus players will likely see an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these champions are able to dish out a surprising amount of magic type damage.

Although, by pairing Karthus and Senna together, you probably will not be granting your other teammates enough engage. Plan to bring other champs on your team that offsets this gap in this pairing's capabilities.

Regardless of the ability of your Senna ally, you should focus on increasing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you will do well anyway.

Additional Information for Karthus Players

How We Calculated Our Karthus Senna Synergy Build and Stats

For this guide on pairing Karthus and Senna, we analyzed 4,177 ranked and recent League of Legends matches. We perform advanced data cleaning and statistical methods to guarantee that our team synergy stats are accurate and reliable. You can be confident that our recommended build to pair Karthus with Senna comes from actual data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view your division's most relevant stats and build.

Other Useful Resources

Further Insights to Win with this Champion Pairing

To truly master Karthus in order to work well with Senna during both the early game and mid / late game phases of League of Legends matches, you should keep reading to gather additional tips and tricks for this champion pairing. If you use the build and stats displayed above, you will increase your win rate significantly.

The most crucial finished items to build first in your Karthus and Senna synergy build include Void Staff, Shadowflame, and Stormsurge. When Karthus incorporated at least these three items in his build, he did a lot better when fighting alongside Senna than with most other commonly used builds. In fact, Karthus boasted an average win rate of 47.0% when synergizing his build and playstyle to Senna with this build.

To have the best probability of beating your oponents, Karthus players should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the runes players picked for Karthus and Senna pairings, this combination of runes resulted in the greatest win rate. In fact, these runes gave a 47.0% win rate overall.

If you want to see Karthus and Senna synergy tips and stats for a an individual division, please choose one from the selection menu shown above. At first, the statistics and guides shown are computed using all rounds completed with these champions.