Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Melee allies can stack Frost for your Permafrost, keep an eye on who they are attacking.
Save Glacial Prison for encounters where you have teammates present to take advantage of it.
Use Arctic Assault to escape bad situations, interupt channeled spells or chase runners.
The Karthus Sejuani synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Sejuani, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Sejuani. His KDA fell from NaN to NaN. This fall shows that Sejuani helps Karthus perform poorer in ranked League of Legends games. Yet, the small difference proves that this performance change is not very impactful.
When Karthus plays on the same team as Sejuani, he gets a little drop in his total damage output. This difference may indicate that Sejuani does not support by providing cover for him to dish out more damage or that her participation also helps extend the match's duration. Similarly, when Karthus is played together with Sejuani on the same team, he usually scores many fewer killing sprees than when he plays without Sejuani. This is contrasting evidence that he is worse when playing with Sejuani.
Additionally, when Karthus plays with Sejuani on the same side, he on average receives much less damage than when he plays alone. Getting dealt not as much damage could indicate that Sejuani does a decent job of protecting Karthus during team fights.
There is no top ally for Karthus that will always be his ideal ally. Yet, overall, Sejuani is a terrible companion for Karthus. By playing on the same team as Karthus, she lowers their win rate by -6.4% to 40.9%. This signals that there is a terrible strategic relationship between Karthus and Sejuani that allows them to perform worse together than without each other.
Sejuani has a much lower diffuclty than Karthus. That means Karthus players don't need to be cautious when arranging Sejuani comrades to go into battle on the same side as, as they will require a much lower level of skill to do well with you.
Playing alongside, you should expect to see an overall large increase in your team’s capability to deal magical damage. Together, these two can blast through enemies with magic damage.
In contrast, by aligning Karthus and Sejuani together, you will not be granting your team a great deal of AD. Plan to include other champions on your team that nullifies this relative hole in this pairing's abilities.
Regardless of your Sejuani ally's ability, you need to focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you heed this simple advice, you should do well, regardless.
If you would like to learn all of the intricacies of Karthus to pair well with Sejuani during both the laning and mid / late game phases of LoL games, you should continue reading to master a few extra lessons on this champion pairing. If you use the build and tips presented above, you will grow your win rate significantly.
The top items to prioritize in your Karthus and Sejuani synergy build include Malignance, Shadowflame, and Liandry's Torment. When Karthus used at least these three finished items in his build, he did a lot better as an ally of Sejuani than with most other common item sets. In fact, Karthus had an average winrate of 40.9% helping carry Sejuani with this build.
To have the best chance of defeating your oponents, Karthus players should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the rune combinations players used for this champion pairing, this sequence of runes resulted in the highest win rate. Notably, these runes averaged a 40.9% win rate overall.
By default, tips, statistics, and builds on how to pair Sejuani with Karthus are given for every ranked division. If you would like to narrow the stats and builds to a specific division, you may use the selection menu at the top of this page.