Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Karthus Samira synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Samira, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Samira. His KDA decreased from NaN to NaN. This worsening shows that Samira helps Karthus perform not as well in competitive League of Legends matches. Yet, the small difference indicates that this performance change is not very impactful.
When Karthus tries to synergize with Samira, he gets a barely noticable drop in his total damage output. This change could signal that Samira doesn't help protection for him to dish out more damage or that her participation also helps increase the game's duration. Similarly, when Karthus is played together with Samira on the same team, he usually scores many fewer killing sprees than when he plays without Samira. This is contrasting evidence that he is worse when playing with Samira.
Moreover, when Karthus plays with Samira on the same side, he on average takes a little more damage than when he fights alone. Getting dealt more damage could mean that Samira does a poor job of protecting Karthus in teamfights.
There is no ideal companion for Karthus that will no matter what be his ideal ally. Yet, overall, Samira is a very typical ally for Karthus. By locking into the same side as Karthus, she decreases their win rate by -0.3% to 47.0%. This clearly indicates that there is only a small strategic relationship between Karthus and Samira that allows them to perform not as well together than alone.
Samira has a lower difficulty than Karthus. That means you don't need to be cautious when lining up Samira allies to fight alongside, as they will require a lower level of skill to fight well with you.
Fighting together, you should witness an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these champions can blast through enemies with magic damage.
Conversely, by pairing Karthus and Samira together, you will not be giving your other teammates a great deal of utility. Plan to pick other champions on your team that offsets this relative hole in their abilities.
Regardless of your Samira ally's ability, you need to focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you should do well anyway.
If you would like to learn all of the intricacies of Karthus to work well with Samira during both the lane and mid / late game phases of League of Legends, you should continue reading to master some more lessons on this champion pairing. If you use the build and stats presented above, you will grow your win rate by a lot.
The ideal items to have in your Karthus and Samira synergy build consist of Rabadon's Deathcap, Void Staff, and Liandry's Torment. When Karthus used at least these three finished items in his build, he did much better when paired up with Samira than with many other common builds. In fact, Karthus had an average win rate of 47.0% when synergizing his build and playstyle to Samira with these items in his kit.
To have the best chance of annihilating your oponents, Karthus players should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the rune combinations we have analyed for this champion pairing, this mix of runes resulted in the best win rate. In fact, these runes provided a 47.0% winrate overall.
If you need to see Karthus and Samira collaboration tips and stats for a an individual division rank, please choose one from the selection menu shown above. By default, the statistics and build suggestions displayed are calculated using all rounds with data with both champs.