Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
While ganking, consider aiming Dredge Line at nearby terrain and following it up with Riptide for a higher hit rate.
Riptide has a delayed blast timing on activation - you can use this while running away or when enemies are incoming to serve as a deterrent.
The Karthus Nautilus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Nautilus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Nautilus. His KDA fell from NaN to NaN. This drop shows that Nautilus helps Karthus perform poorer in competitive League matches. Yet, the small difference indicates that this performance change is only marginal.
When Karthus plays on the same team as Nautilus, he sees a small increase in his complete damage dealt. This could demonstrate that Nautilus provides cover for him to deal more damage or that his allyship also helps extend the match's duration. Similarly, when Karthus is played together with Nautilus on the same team, he usually scores many fewer killing sprees compared to when he plays on his own. This is contrasting evidence that he is worse when playing alongside Nautilus.
Moreover, when Karthus plays with Nautilus on the same team, he usually receives a little less damage than when he fights alone. Receiving not as much damage may mean that Nautilus does a decent job of protecting Karthus during team fights.
There is no ideal ally for Karthus that will 100% of the time be his top teammate. However, Nautilus is a decent teammate for Karthus. By locking into the same team as Karthus, he improves their win rate by 1.5% to 48.8%. This shows that there is pretty good bond between Karthus and Nautilus that results in them performing stronger together than alone.
Nautilus has a lower difficulty than Karthus. That means you don't need to be careful when finding Nautilus comrades to go into battle on the same side as, as they will have to have a relatively low level of skill to play well with you.
Fighting alongside, you will likely see an overall large increase in your team’s ability to deal magical damage. When paired, these champions are able to dish out a surprising amount of magic type damage.
Although, by pairing Karthus and Nautilus together, you will not be giving your other allies very much AD. Plan to bring other champions on your team that offsets this disparity in their abilities.
Regardless of the skill of your Nautilus ally, you should focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you should do well, regardless.
To learn all of the intricacies of Karthus in order to pair well with Nautilus during both the laning and mid / late game phases of League of Legends rounds, you should keep reading to learn a few extra tips and tricks for this champion pairing. If you listen to the build and suggestions shown here, you should grow your win rate by a lot.
The best items to use in your Karthus and Nautilus synergy build consist of Rabadon's Deathcap, Shadowflame, and Stormsurge. When Karthus used at least these three finished items in his build, he did significantly better when paired up with Nautilus than with most other common builds. In fact, Karthus had an average win rate of 48.8% when synergizing his build and playstyle to Nautilus with these items in his kit.
To have the greatest likelihood of vanquishing your oponents, you should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Of all the rune combinations players picked for this team composition, this composite of runes yielded the best win rate. Moreover, these runes averaged a 48.8% win rate overall.
By default, tips, stats, and builds on how to synergize Nautilus with Karthus are displayed for every ranked division. If you would like to scope the statistics and builds to an individual rank, you can use the selection menu at the top of this page.