Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Enemies are considered isolated if they have no allies within a short distance. The damage of Taste Their Fear is massively increased against these targets.
Unseen Threat activates when Kha'Zix cannot be seen by the enemy team. Reactivate by using brush or Void Assault. Don't forget to apply Unseen Threat by autoattacking enemy champions.
Kha'Zix has a great deal of freedom to choose where and when to fight. Pick your battles carefully to succeed.
The Karthus Kha'Zix synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Kha'Zix, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Kha'Zix. His KDA fell from NaN to NaN. This decrease shows that Kha'Zix helps Karthus perform not as well in ranked League of Legends games. Yet, the small difference proves that this performance change is only marginal.
When Karthus plays on the same team as Kha'Zix, he observes a little increase in his complete damage output. This change may indicate that Kha'Zix supports by providing cover for him to deal more damage or that his support also helps increase the match's duration. Similarly, when Karthus is played with Kha'Zix on the same team, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing with Kha'Zix.
Moreover, when Karthus plays with Kha'Zix on the same side, he usually receives much less damage than when he plays alone. Taking not as much damage may indicate that Kha'Zix does a decent job of covering Karthus in teamfights.
There is no perfect champion pairing for Karthus that will always be his #1 synergy. However, Kha'Zix is a decent companion for Karthus. By playing on the same side as Karthus, he raises their win rate by 1.8% to 49.1%. This shows that there is a somewhat important synergy between Karthus and Kha'Zix that allows them to perform better together than without each other.
Kha'Zix has a lower difficulty than Karthus. That means you don't need to be careful when lining up Kha'Zix teammates to go into battle on the same side as, as they will require a relatively low level of skill to cooperate well with you.
When playing together, you will likely observe an overall large increase in your team’s ability to deal magic damage. When paired, these champs can deal quite a lot of AP type damage.
Conversely, by pairing Karthus and Kha'Zix together, you probably will not be granting your side enough tankyness. Plan to include other champs on your team that neutralizes this gap in this pairing's capabilities.
Regardless of the skill of your Kha'Zix teammate, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you should do well, regardless.
To truly master Karthus in order to work well with Kha'Zix during both the laning and mid / late game phases of League of Legends rounds, you should keep reading to pick up some more tricks and insights into this champion pairing. If you use the build and stats presented above, you will increase your win rate by a lot.
The ideal items to include in your Karthus and Kha'Zix synergy build consist of Rabadon's Deathcap, Malignance, and Shadowflame. When Karthus included at least these three items in his build, he did significantly better when paired up with Kha'Zix than with most other common item sets. In fact, Karthus had an average winrate of 49.1% helping carry Kha'Zix with these items in his kit.
To have the greatest chance of defeating your oponents, you should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the rune builds we have analyed for this champion pairing, this combination of runes resulted in the best win rate. Moreover, these runes gave a 49.1% winrate overall.
By default, tips, stats, and builds on how to team up Kha'Zix with Karthus are given for all skill levels, merged. If you would like to narrow the stats and builds to a particular skill level, you can use the selection menu located earlier on the page.