Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Rend is a valuable last hitting aid, since its cooldown resets if it kills a target.
Entering a move order once to trigger Martial Poise will not clear Kalista's basic attack target.
Due to her passive, Kalista's Move Speed is effectively increased by Attack Speed.
The Karthus Kalista synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Kalista, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Kalista. His KDA worsened from NaN to NaN. This fall shows that Kalista helps Karthus perform not as well in competitive LoL rounds. Yet, the small difference indicates that this performance change is not very impactful.
When Karthus is an ally to Kalista, he gets a marginal improvement in his total damage output. This difference may indicate that Kalista provides cover for him to deal more damage or that her presence on the team also helps extend the game's duration. Similarly, when Karthus is played together with Kalista on the same team, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing with Kalista.
Moreover, when Karthus plays with Kalista on the same side, he on average takes a little more damage than when he plays alone. Taking more damage could mean that Kalista does a poor job of protecting Karthus in team fights.
There is no ideal companion for Karthus that will no matter what be his top teammate. Yet, overall, Kalista is a terrible ally for Karthus. By locking into the same side as Karthus, she decreases their win rate by -3.2% to 44.1%. This proves that there is a very bad synergy between Karthus and Kalista that allows them to perform not as well together than without each other.
Kalista has a lower difficulty than Karthus. That means Karthus players don't need to be careful when lining up Kalista comrades to fight alongside, as they will have to have a lower level of skill to be able to work well with you.
Playing cooperatively, you will likely see an overall large increase in your team’s capacity to to do a lot of AP damage. Combined, these champions are able to dish out a surprising amount of magic type damage.
Conversely, by grouping Karthus and Kalista together, you probably will not be granting your team much tankyness. Make sure to have other champions on your team that neutralizes this relative gap in this pairing's abilities.
Regardless of your Kalista ally's skill level, you should focus on increasing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you will do well anyway.
If you would like to learn all of the intricacies of Karthus to pair well with Kalista during both the lane and mid / late game phases of League of Legends matches, you should keep reading to learn additional tips and tricks for this champion pairing. If you listen to the build and suggestions shown above, you will grow your win rate by a lot.
The most crucial finished items to include in your Karthus and Kalista synergy build consist of Rabadon's Deathcap, Shadowflame, and Liandry's Torment. When Karthus used at least these three items in his build, he performed significantly better when paired up with Kalista than with most other commonly used item sets. In fact, Karthus boasted an average win rate of 44.1% helping carry Kalista with this build.
To have the highest chance of coming out on top against your oponents, Karthus players should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the rune combinations that we analyzed for Karthus and Kalista pairings, this set of runes resulted in the best win rate. Moreover, these runes averaged a 44.1% winrate overall.
By default, tips, stats, and builds on how to synergize Kalista with Karthus are displayed for all ranked divisions. If you want to filter the statistics and builds to an individual division, you should use the selection menu located above.