Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Elise's Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
When in Spider Form, Spiderlings will attack the target that Elise uses Venomous Bite on.
The Karthus Elise synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Elise, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Elise. His KDA fell from NaN to NaN. This drop shows that Elise helps Karthus perform not as well in ranked League of Legends matches. Yet, the small difference demonstrates that this performance change is not very impactful.
When Karthus is an ally to Elise, he sees a moderate decrease in his total damage dealt. This may signal that Elise does not support by providing protection for him to dish out more damage or that her participation also helps increase the match's duration. Similarly, when Karthus is played alongside Elise on the same side, he usually scores many fewer killing sprees than when he plays without Elise. This is contrasting evidence that he is worse when playing with Elise.
Additionally, when Karthus plays with Elise on the same side, he on average takes much less damage than when he fights alone. Receiving not as much damage could mean that Elise does a decent job of covering Karthus during team fights.
There is no top synergy for Karthus that will always be his #1 synergy. Yet, Elise is a not very good companion for Karthus. By being on the same team as Karthus, she lowers their win rate by -2.5% to 44.8%. This proves that there is a negative strategic relationship between Karthus and Elise that results in them performing worse together than without each other.
Elise has a greater difficulty than Karthus. That means Karthus players should be cautious when finding Elise allies to go into battle on the same side as, as they will need a greater level of skill to fight well with you.
Fighting cooperatively, Karthus players will likely observe an overall large increase in your team’s ability to to do a lot of AP damage. Together, these champions are able to dish out a surprising amount of magic type damage.
Although, by bringing Karthus and Elise together, you may not be providing your side much tankyness. Plan to pick other champs on your team that neutralizes this gap in their kit.
Regardless of your Elise ally's skill level, you should focus on increasing your gold income, outlasting your enemies, and taking down objectives. If you heed this simple advice, you should do well anyway.
If you would like to truly master Karthus to synergize with Elise during both the lane and mid / late game phases of League, you should continue reading to gather additional tips and tricks for this champion pairing. If you listen to the build and suggestions displayed here, you will grow your win rate significantly.
The ideal finished items to build first in your Karthus and Elise synergy build consist of Rabadon's Deathcap, Cryptbloom, and Shadowflame. When Karthus bought at least these three items in his build, he performed a lot better when fighting alongside Elise than with most other typical item sets. In fact, Karthus had an average winrate of 44.8% when playing alongside Elise with these items in his kit.
To have the best likelihood of defeating your oponents, Karthus players should take the Dark Harvest, Cheap Shot, Eyeball Collection, Treasure Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the runes players chose for this team composition, this sequence of runes resulted in the highest win rate. Notably, these runes gave a 44.8% winrate overall.
If you want to get Karthus with Elise cooperations tips and stats for a a distinct skill level, please select one from the selection menu above. By default, the stats and strategies shown are computed using all rounds run with these champs.