Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Fire 90 Caliber Net away from the opponent to close the gap or hop over walls.
Avoid using Ace in the Hole in large team melees as it might be blocked by the wrong target.
Make use of her Yordle Snap Traps by placing them pre-emptively to ensure that you'll have one off of cooldown during combat.
The Karthus Caitlyn synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Caitlyn, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Caitlyn. His KDA decreased from NaN to NaN. This decrease shows that Caitlyn helps Karthus perform poorer in ranked League rounds. Yet, the small difference demonstrates that this performance change is not very impactful.
When Karthus tries to synergize with Caitlyn, he gets a little drop in his complete damage output. This could demonstrate that Caitlyn does not provide protection for him to dish out more damage or that her support also helps extend the round's duration. Similarly, when Karthus is played alongside Caitlyn on the same team, he usually scores many fewer killing sprees compared to when he plays on his own. This is contrasting evidence that he is worse when playing alongside Caitlyn.
Moreover, when Karthus plays with Caitlyn on the same team, he usually receives a little more damage than when he plays alone. Receiving more damage could mean that Caitlyn does a poor job of covering Karthus in teamfights.
There is no top synergy for Karthus that will 100% of the time be his #1 synergy. Yet, Caitlyn is a very typical teammate for Karthus. By locking into the same team as Karthus, she raises their win rate by 0.1% to 47.4%. This shows that there is not really a strong strategic relationship between Karthus and Caitlyn that allows them to perform better together than without each other.
Caitlyn has a lower difficulty than Karthus. That means you don't need to be very careful when finding Caitlyn comrades to go into battle on the same side as, as they will have to have a lower level of skill to cooperate well with you.
Playing cooperatively, Karthus players should see an overall large increase in your team’s ability to to do a lot of AP damage. When paired, these champs can deal quite a lot of AP type damage.
In contrast, by pairing Karthus and Caitlyn together, you may not be providing your other allies a lot of engage. Plan to bring other champions on your team that helps cover this gap in their abilities.
Regardless of your Caitlyn ally's skill level, you should focus on increasing your income, staying alive by avoiding foolish fights, and clearing objectives. If you follow these simple suggestions, you will do well anyway.
To truly master Karthus in order to pair well with Caitlyn during both the lane and mid / late game phases of League matches, you should keep reading to pick up some more tips and tricks for this champion pairing. If you mind the build and suggestions displayed here, you should increase your win rate significantly.
The most important items to get in your Karthus and Caitlyn synergy build include Rabadon's Deathcap, Malignance, and Zhonya's Hourglass. When Karthus used at least these three items in his build, he did much better as an ally of Caitlyn than with many other typical item sets. In fact, Karthus boasted an average winrate of 47.4% when synergizing his build and playstyle to Caitlyn with these items in his kit.
To have the best chance of beating your oponents, you should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the rune combinations that we analyzed for this champion pairing, this sequence of runes resulted in the greatest win rate. In fact, these runes provided a 47.4% winrate overall.
If you want to view Karthus and Caitlyn synergy tips and stats for a an individual division, please choose one from the selection menu displayed above. If viewing for the first time, the statistics and build suggestions given are computed using every match with data with both champions.