Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
Sleepy Trouble Bubble travels further over walls. Find a hiding spot to set up for a long distance kill.
Break Sleep with your biggest damage source, since enemies who are asleep take double damage.
Paddle Star deals more damage the further it has flown. Casting it behind yourself before redirecting can deal tons of damage.
The Kai'Sa Zoe synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Zoe, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Zoe. His KDA went down from NaN to NaN. This fall shows that Zoe helps Kai'Sa perform not as well in ranked LoL matches. Yet, the small difference shows that this performance change is only marginal.
When Kai'Sa plays on the same team as Zoe, she gets a little drop in her complete damage dealt. This may indicate that Zoe does not help protection for her to dish out more damage or that her allyship also helps extend the match's duration. Similarly, when Kai'Sa is played together with Zoe on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing alongside Zoe.
Moreover, when Kai'Sa plays with Zoe on the same side, she on average receives a little less damage than when she fights alone. Getting dealt not as much damage may mean that Zoe does a decent job of covering Kai'Sa during teamfights.
There is no universally accepted best champion pairing for Kai'Sa that will always be her best ally. However, overall, Zoe is a relatively poor companion for Kai'Sa. By locking into the same team as Kai'Sa, she lowers their win rate by -2.4% to 44.1%. This proves that there is a negative bond between Kai'Sa and Zoe that results in them performing worse together than without each other.
Zoe has a lower difficulty than Kai'Sa. That means Kai'Sa players don't need to be very careful when enlisting Zoe teammates to play with, as they will need a relatively low level of skill to be able to fight well with you.
When playing on the same side, you should expect to see an overall large increase in your team’s capability to soak up damage. Combined, these champions will be able to tank for the rest of their team.
Conversely, by bringing Kai'Sa and Zoe together, you will not be giving your other teammates very much utility. Plan to pick other champions on your team that fills this relative disparity in their capabilities.
Regardless of your Zoe ally's skill level, you should focus on maximizing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you will do well, regardless.
To learn all of the intricacies of Kai'Sa in order to synergize with Zoe during both the early game and mid / late game phases of League of Legends, you should continue reading to pick up some more tricks and insights into this champion pairing. If you mind the build and stats presented here, you will grow your win rate significantly.
The top finished items to have in your Kai'Sa and Zoe synergy build consist of Terminus, Kraken Slayer, and Navori Quickblades. When Kai'Sa included at least these three finished items in her build, she did much better when paired up with Zoe than with most other typical item sets. In fact, Kai'Sa had an average win rate of 44.1% when synergizing her build and playstyle to Zoe with this build.
To have the highest likelihood of vanquishing your oponents, Kai'Sa players should take the Hail of Blades, Taste of Blood, Eyeball Collection, Treasure Hunter, Biscuit Delivery, and Magical Footwear runes from the Domination and Inspiration rune sets. Of all the rune builds players used for this team composition, this mix of runes yielded the best win rate. Notably, these runes averaged a 44.1% win rate overall.
By default, tips, stats, and builds on how to team up Zoe with Kai'Sa are presented for all skill levels combined. To scope the stats and builds to a distinct rank, you can use the selection menu located at the top of this page.