Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
The Kai'Sa Zilean synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Zilean, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Zilean. His KDA went down from NaN to NaN. This drop shows that Zilean helps Kai'Sa perform poorer in competitive League games. Yet, the small difference shows that this performance change is not very impactful.
When Kai'Sa plays on the same team as Zilean, she observes a little increase in her full damage dealt. This difference may signal that Zilean supports by providing cover for her to deal more damage or that his allyship also helps increase the game's duration. Similarly, when Kai'Sa is played together with Zilean on the same team, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Zilean.
Moreover, when Kai'Sa plays with Zilean on the same side, she usually receives more damage than when she plays alone. Receiving more damage could indicate that Zilean does a poor job of covering Kai'Sa during teamfights.
There is no one best synergy for Kai'Sa that will no matter what be her top synergy. Yet, overall, Zilean is a very typical ally for Kai'Sa. By playing on the same side as Kai'Sa, he increases their win rate by 0.3% to 46.8%. This demonstrates that there is a weak strategic relationship between Kai'Sa and Zilean that results in them performing at the top of their game together than alone.
Zilean has a lower difficulty than Kai'Sa. That means you don't need to be very careful when finding Zilean comrades to go into battle on the same side as, as they will have to have a lower level of skill to be able to cooperate well with you.
Fighting alongside, you will likely see an overall large increase in your team’s capacity to to do a lot of AP damage. Combined, these two can blast through enemies with magic damage.
In contrast, by aligning Kai'Sa and Zilean together, you may not be providing your other teammates a great deal of crowd control. We recommend you have other champions on your team that nullifies this disparity in their potential.
Regardless of your Zilean ally's ability, you need to focus on maximizing your income, warding to avoid ambushes, and taking down objectives. If you do this, you will do well anyway.
To truly master Kai'Sa to pair well with Zilean during both the early game and mid / late game phases of League matches, you should keep reading to learn a few extra lessons on this champion pairing. If you listen to the build and stats presented above, you will increase your win rate significantly.
The ideal items to focus on in your Kai'Sa and Zilean synergy build consist of Terminus, Kraken Slayer, and Navori Quickblades. When Kai'Sa used at least these three pieces in her build, she performed a lot better when paired up with Zilean than with many other typical item sets. In fact, Kai'Sa had an average winrate of 46.8% when playing alongside Zilean with this build.
To have the highest likelihood of coming out on top against your oponents, Kai'Sa players should take the Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the rune combinations players used for this champion pairing, this combo of runes resulted in the greatest win rate. Moreover, these runes provided a 46.8% win rate overall.
By default, tips, stats, and builds on how to team up Zilean with Kai'Sa are presented for all skill levels combined. If you would like to scope the stats and builds to an individual player tier, you can use the selection menu earlier on the page.