Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
The Kai'Sa Vladimir synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Vladimir, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Vladimir. His KDA went down from NaN to NaN. This fall shows that Vladimir helps Kai'Sa perform poorer in ranked League of Legends rounds. Yet, the small difference indicates that this performance change is only marginal.
When Kai'Sa plays on the same team as Vladimir, she observes a barely noticable drop in her complete damage dealt. This may signal that Vladimir does not help protection for her to dish out more damage or that his participation also helps extend the game's duration. Similarly, when Kai'Sa is played with Vladimir on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing alongside Vladimir.
Additionally, when Kai'Sa plays with Vladimir on the same team, she usually receives a little less damage than when she fights alone. Getting dealt not as much damage could mean that Vladimir does a decent job of covering Kai'Sa in team fights.
There is no universally accepted best synergy for Kai'Sa that will no matter what be her top synergy. Yet, overall, Vladimir is a below average teammate for Kai'Sa. By playing on the same team as Kai'Sa, he drops their win rate by -1.1% to 45.4%. This proves that there is a bad bond between Kai'Sa and Vladimir that results in them performing worse together than alone.
Vladimir has a greater difficulty than Kai'Sa. That means you need to be very careful when lining up Vladimir teammates to fight alongside, as they will need a greater level of skill to fight well with you.
Playing alongside, you should expect to witness an overall large increase in your team’s ability to deal magical damage. When paired, these champions can blast through enemies with magic damage.
Although, by bringing Kai'Sa and Vladimir together, you will not be providing your other teammates a great deal of utility. Make sure to have other champions on your team that fills this hole in this pairing's abilities.
Regardless of the ability of your Vladimir teammate, you should focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you follow these simple suggestions, you should do well, regardless.
To learn all of the intricacies of Kai'Sa to synergize with Vladimir during both the laning and mid / late game phases of LoL games, you should continue reading to learn a few extra tricks and insights into this champion pairing. If you pay attention to the build and suggestions shown above, you will increase your win rate significantly.
The best items to have in your Kai'Sa and Vladimir synergy build consist of Guardian Angel, Terminus, and Kraken Slayer. When Kai'Sa bought at least these three finished items in her build, she performed much better when fighting alongside Vladimir than with many other typical item sets. In fact, Kai'Sa boasted an average winrate of 45.4% when synergizing her build and playstyle to Vladimir with these items in her kit.
To have the highest chance of crushing your oponents, Kai'Sa players should use the Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the rune combinations players used for Kai'Sa and Vladimir pairings, this combo of runes resulted in the best win rate. Notably, these runes averaged a 45.4% winrate overall.
By default, tips, stats, and builds on how to pair Vladimir with Kai'Sa are presented for all skill levels, merged. To filter the stats and builds to a distinct skill level, you may use the selection menu at the top of this page.