Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
The Kai'Sa Sett synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Sett, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Sett. His KDA decreased from NaN to NaN. This fall shows that Sett helps Kai'Sa perform not as well in competitive League of Legends matches. Yet, the small difference proves that this performance change is only marginal.
When Kai'Sa is paired with Sett, she observes a little drop in her full damage output. This difference could indicate that Sett does not provide cover for her to dish out more damage or that his participation also helps increase the game's duration. Similarly, when Kai'Sa is played alongside Sett on the same team, he usually scores many fewer killing sprees than when she plays without Sett. This is contrasting evidence that she is worse when playing alongside Sett.
Additionally, when Kai'Sa plays with Sett on the same team, she on average takes a little less damage than when she plays alone. Getting dealt not as much damage could indicate that Sett does a decent job of protecting Kai'Sa in teamfights.
There is no universally accepted best companion for Kai'Sa that will no matter what be her #1 ally. However, overall, Sett is a decent ally for Kai'Sa. By playing on the same team as Kai'Sa, he raises their win rate by 1.0% to 47.5%. This demonstrates that there is a somewhat important strategic relationship between Kai'Sa and Sett that allows them to perform better together than alone.
Sett has a much lower diffuclty than Kai'Sa. That means Kai'Sa players don't need to be careful when finding Sett comrades to fight alongside, as they will require a much lower level of skill to work well with you.
Working together, Kai'Sa players should expect to see an overall large increase in your team’s capability to deal physical damage. Combined, these champions can tear through the other team with a lot of physcial damage.
In contrast, by aligning Kai'Sa and Sett together, you will not be granting your other allies much crowd control. Plan to pick other champions on your team that neutralizes this hole in this pairing's potential.
Regardless of your Sett ally's ability, you need to focus on increasing your gold income, outlasting your enemies, and taking down objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Kai'Sa in order to pair well with Sett during both the early game and mid / late game phases of League of Legends matches, you should keep reading to pick up additional tricks and insights into this champion pairing. If you listen to the build and suggestions displayed above, you will grow your win rate significantly.
The best finished items to prioritize in your Kai'Sa and Sett synergy build include Guinsoo's Rageblade, Zhonya's Hourglass, and Kraken Slayer. When Kai'Sa incorporated at least these three pieces in her build, she did significantly better when paired up with Sett than with many other common builds. In fact, Kai'Sa had an average win rate of 47.5% when synergizing her build and playstyle to Sett with these items in her kit.
To have the highest probability of vanquishing your oponents, you should use the Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the rune sets players picked for this champion pairing, this order of runes resulted in the top win rate. Notably, these runes provided a 47.5% winrate overall.
By default, tips, stats, and builds on how to pair Sett with Kai'Sa are displayed for all ranked divisions. If you want to filter the stats and builds to an individual division, you may use the selection menu at the top of this page.