Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
The Kai'Sa Neeko synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Neeko, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Neeko. His KDA fell from NaN to NaN. This negative change shows that Neeko helps Kai'Sa perform worse in competitive LoL rounds. Yet, the small difference indicates that this performance change is not very impactful.
When Kai'Sa is paired with Neeko, she sees a little increase in her total damage output. This could indicate that Neeko provides protection for her to deal more damage or that her allyship also helps extend the match's duration. Similarly, when Kai'Sa is played with Neeko on the same side, he usually scores many fewer killing sprees than when she plays without Neeko. This is contrasting evidence that she is worse when playing alongside Neeko.
Moreover, when Kai'Sa plays with Neeko on the same team, she typically receives a little more damage than when she fights alone. Receiving more damage may indicate that Neeko does a poor job of protecting Kai'Sa during team fights.
There is no top champion pairing for Kai'Sa that will no matter what be her top synergy. Yet, overall, Neeko is a very typical ally for Kai'Sa. By playing on the same team as Kai'Sa, she decreases their win rate by -0.3% to 46.2%. This proves that there is a weak bond between Kai'Sa and Neeko that allows them to perform worse together than alone.
Neeko has a lower difficulty than Kai'Sa. That means Kai'Sa players don't need to be careful when finding Neeko comrades to go into battle on the same side as, as they will have to have a lower level of skill to be able to cooperate well with you.
Working cooperatively, Kai'Sa players will likely observe an overall large increase in your team’s capacity to to do a lot of AP damage. Together, these champions are able to dish out a surprising amount of magic type damage.
Conversely, by aligning Kai'Sa and Neeko together, you probably will not be giving your other teammates much support. Plan to include other champions on your team that offsets this gap in this pairing's abilities.
Regardless of the skill of your Neeko ally, you need to focus on increasing your income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you will do well anyway.
If you would like to truly master Kai'Sa in order to work well with Neeko during both the early game and mid / late game phases of League of Legends games, you should continue reading to master a few extra lessons on this champion pairing. If you pay attention to the build and suggestions presented here, you will grow your win rate by a lot.
The most important finished items to prioritize in your Kai'Sa and Neeko synergy build include Phantom Dancer, Kraken Slayer, and Navori Quickblades. When Kai'Sa included at least these three items in her build, she did a lot better when fighting alongside Neeko than with many other common item sets. In fact, Kai'Sa had an average win rate of 46.2% when playing alongside Neeko with this build.
To have the highest probability of annihilating your oponents, Kai'Sa players should take the Hail of Blades, Taste of Blood, Eyeball Collection, Treasure Hunter, Biscuit Delivery, and Magical Footwear runes from the Domination and Inspiration rune sets. Out of all the rune sets that we analyzed for Kai'Sa and Neeko pairings, this order of runes yielded the highest win rate. In fact, these runes provided a 46.2% win rate overall.
By default, tips, statistics, and builds on how to pair Neeko with Kai'Sa are given for every ranked division. If you want to filter the statistics and builds to a particular skill level, you can use the selection menu located earlier on the page.