Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
Enemies are considered isolated if they have no allies within a short distance. The damage of Taste Their Fear is massively increased against these targets.
Unseen Threat activates when Kha'Zix cannot be seen by the enemy team. Reactivate by using brush or Void Assault. Don't forget to apply Unseen Threat by autoattacking enemy champions.
Kha'Zix has a great deal of freedom to choose where and when to fight. Pick your battles carefully to succeed.
The Kai'Sa Kha'Zix synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Kha'Zix, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Kha'Zix. His KDA worsened from NaN to NaN. This decrease shows that Kha'Zix helps Kai'Sa perform not as well in ranked League games. Yet, the small difference indicates that this performance change is only marginal.
When Kai'Sa plays on the same team as Kha'Zix, she sees a barely noticable drop in her full damage dealt. This could demonstrate that Kha'Zix does not help cover for her to deal more damage or that his participation also helps extend the game's duration. Similarly, when Kai'Sa is played together with Kha'Zix on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing with Kha'Zix.
Additionally, when Kai'Sa plays with Kha'Zix on the same side, she on average receives a little more damage than when she fights alone. Receiving more damage could indicate that Kha'Zix does a poor job of protecting Kai'Sa during teamfights.
There is no perfect synergy for Kai'Sa that will 100% of the time be her top synergy. However, Kha'Zix is a very typical teammate for Kai'Sa. By locking into the same team as Kai'Sa, he drops their win rate by -0.5% to 46.0%. This proves that there is a weak synergy between Kai'Sa and Kha'Zix that allows them to perform not as well together than without each other.
Kha'Zix has a lower difficulty than Kai'Sa. That means Kai'Sa players don't need to be cautious when lining up Kha'Zix teammates to play with, as they will need a lower level of skill to be able to work well with you.
Working together, Kai'Sa players will likely see an overall large increase in your team’s capacity to dish out massive AD. When paired, these two can provide a great amount of sustained physical damage.
In contrast, by aligning Kai'Sa and Kha'Zix together, you probably will not be granting your other teammates enough support. Make sure to include other champions on your team that helps cover this relative hole in their kit.
Regardless of your Kha'Zix ally's skill level, you should focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you heed this simple advice, you will do well anyway.
If you would like to learn all of the intricacies of Kai'Sa in order to synergize with Kha'Zix during both the laning and mid / late game phases of League of Legends matches, you should keep reading to learn some more lessons on this champion pairing. If you mind the build and suggestions presented above, you should increase your win rate significantly.
The most crucial items to have in your Kai'Sa and Kha'Zix synergy build include Phantom Dancer, Kraken Slayer, and Navori Quickblades. When Kai'Sa combined at least these three great items in her build, she did a lot better when paired up with Kha'Zix than with most other typical builds. In fact, Kai'Sa had an average winrate of 46.0% when synergizing her build and playstyle to Kha'Zix with these items in her kit.
To have the greatest probability of annihilating your oponents, Kai'Sa players should take the Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace, Magical Footwear, and Biscuit Delivery runes from the Precision and Inspiration rune sets. Out of all the rune sets that we analyzed for this champion pairing, this composite of runes yielded the best win rate. Moreover, these runes gave a 46.0% win rate overall.
By default, tips, stats, and builds on how to pair Kha'Zix with Kai'Sa are shown for all ranked divisions. If you would like to scope the stats and builds to a specific skill level, you can use the selection menu located at the top of this page.