Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
Don't be too conservative with Mantra. Gathering Fire is strongest in teamfights, making it easy to recharge Mantra multiple times.
Gathering Fire rewards aggressive play. Look to land abilities and basic attacks on your opponent to lower Mantra's cooldown and stay on the offensive.
When using Focused Resolve, slow your opponents with Inner Flame or speed yourself up with Inspire if you're having trouble sticking to a target.
The Kai'Sa Karma synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karma, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Kai'Sa sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karma. His KDA decreased from NaN to NaN. This negative change shows that Karma helps Kai'Sa perform worse in ranked League rounds. Yet, the small difference shows that this performance change is not very impactful.
When Kai'Sa is paired with Karma, she gets a little increase in her complete damage output. This difference may demonstrate that Karma supports by providing protection for her to dish out more damage or that her presence on the team also helps increase the game's duration. Similarly, when Kai'Sa is played with Karma on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing with Karma.
Additionally, when Kai'Sa plays with Karma on the same side, she usually takes a little less damage than when she fights alone. Getting dealt not as much damage could mean that Karma does a decent job of covering Kai'Sa during teamfights.
There is no perfect synergy for Kai'Sa that will always be her top synergy. Yet, overall, Karma is a below average teammate for Kai'Sa. By locking into the same side as Kai'Sa, she decreases their win rate by -1.8% to 44.7%. This proves that there is a harmful synergy between Kai'Sa and Karma that allows them to perform not as well together than alone.
Karma has a lower difficulty than Kai'Sa. That means you don't need to be very careful when arranging Karma teammates to go into battle on the same side as, as they will need a lower level of skill to be able to fight well with you.
When playing together, you should witness an overall large increase in your team’s capacity to tank a lot of damage. When paired, these champs will be a great protective duo.
Conversely, by pairing Kai'Sa and Karma together, you will not be providing your team a lot of utility. We recommend you include other champions on your team that neutralizes this relative disparity in this pairing's playstyle.
Regardless of the skill of your Karma ally, you should focus on maximizing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you will do well anyway.
If you would like to truly master Kai'Sa to synergize with Karma during both the laning and mid / late game phases of League of Legends games, you should keep reading to gather additional lessons on this champion pairing. If you listen to the build and stats shown here, you will grow your win rate significantly.
The top items to have in your Kai'Sa and Karma synergy build include Guinsoo's Rageblade, Zhonya's Hourglass, and Kraken Slayer. When Kai'Sa included at least these three items in her build, she did a lot better as an ally of Karma than with most other typical item sets. In fact, Kai'Sa boasted an average winrate of 44.7% helping carry Karma with these items in her kit.
To have the highest probability of annihilating your oponents, Kai'Sa players should use the Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the runes players picked for Kai'Sa and Karma pairings, this composite of runes resulted in the best win rate. Moreover, these runes averaged a 44.7% win rate overall.
If you would like to view Kai'Sa and Karma collaboration tips and stats for a an individual division rank, please choose one from the selection menu shown above. At first, the stats and guides given are computed using all matches run with both champs.