Use Arcane Shift to help line up your other skill shots.
You can line up Trueshot Barrage to hit multiple minion waves or even Monsters.
You can play Ezreal either as a Attack Damage carry or Ability Power carry depending on how you build him.
The Ezreal Seraphine synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Seraphine, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Ezreal sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Seraphine. His KDA worsened from NaN to NaN. This drop shows that Seraphine helps Ezreal perform worse in competitive League of Legends matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Ezreal is an ally to Seraphine, he observes a little decrease in his total damage dealt. This difference could demonstrate that Seraphine doesn't help protection for him to deal more damage or that her allyship also helps increase the round's duration. Similarly, when Ezreal is played alongside Seraphine on the same side, he usually scores many fewer killing sprees compared to when he plays without Seraphine. This is contrasting evidence that he is worse when playing alongside Seraphine.
Additionally, when Ezreal plays with Seraphine on the same team, he typically takes a little less damage than when he plays alone. Receiving not as much damage may indicate that Seraphine does a decent job of protecting Ezreal in team fights.
There is no top ally for Ezreal that will always be his #1 teammate. However, overall, Seraphine is a relatively poor companion for Ezreal. By being on the same team as Ezreal, she drops their win rate by -1.6% to 45.3%. This proves that there is a bad bond between Ezreal and Seraphine that results in them performing worse together than without each other.
Seraphine has a much lower diffuclty than Ezreal. That means Ezreal players don't need to be careful when finding Seraphine teammates to fight alongside, as they will need a much lower level of skill to be able to play well with you.
When playing alongside, Ezreal players will likely witness an overall large increase in your team’s ability to buff allies and debuff enemies. When paired, these champs will help their other teammates secure a victory.
In contrast, by grouping Ezreal and Seraphine together, you may not be granting your side very much cover. Make sure to have other champs on your team that nullifies this gap in this pairing's abilities.
Regardless of your Seraphine ally's ability, you need to focus on increasing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you should do well, regardless.
If you would like to truly master Ezreal in order to pair well with Seraphine during both the lane and mid / late game phases of League games, you should continue reading to master additional tricks and insights into this champion pairing. If you use the build and suggestions displayed above, you will increase your win rate by a lot.
The most crucial items to have in your Ezreal and Seraphine synergy build consist of Lord Dominik's Regards, Muramana, and Navori Quickblades. When Ezreal incorporated at least these three great items in his build, he performed a lot better when fighting alongside Seraphine than with many other common item sets. In fact, Ezreal had an average win rate of 45.3% when playing alongside Seraphine with this build.
To have the best chance of annihilating your oponents, you should use the Press the Attack, Presence of Mind, Legend: Bloodline, Coup de Grace, Magical Footwear, and Biscuit Delivery runes from the Precision and Inspiration rune sets. Of all the runes players used for this champion pairing, this blending of runes resulted in the highest win rate. Notably, these runes provided a 45.3% winrate overall.
By default, tips, stats, and builds on how to synergize Seraphine with Ezreal are shown for all skill levels combined. To narrow the stats and builds to a distinct rank, you may use the selection menu earlier in the counter matchup guide.