Use Arcane Shift to help line up your other skill shots.
You can line up Trueshot Barrage to hit multiple minion waves or even Monsters.
You can play Ezreal either as a Attack Damage carry or Ability Power carry depending on how you build him.
While ganking, consider aiming Dredge Line at nearby terrain and following it up with Riptide for a higher hit rate.
Riptide has a delayed blast timing on activation - you can use this while running away or when enemies are incoming to serve as a deterrent.
The Ezreal Nautilus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Nautilus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Ezreal sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Nautilus. His KDA fell from NaN to NaN. This negative change shows that Nautilus helps Ezreal perform worse in ranked League rounds. Yet, the small difference shows that this performance change is not very impactful.
When Ezreal plays on the same team as Nautilus, he sees a little increase in his full damage dealt. This difference could signal that Nautilus helps provide cover for him to dish out more damage or that his participation also helps extend the match's duration. Similarly, when Ezreal is played with Nautilus on the same side, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing alongside Nautilus.
Additionally, when Ezreal plays with Nautilus on the same side, he usually takes a little less damage than when he fights alone. Receiving not as much damage may indicate that Nautilus does a decent job of protecting Ezreal during team fights.
There is no ideal companion for Ezreal that will always be his ideal synergy. However, overall, Nautilus is a terrible ally for Ezreal. By being on the same side as Ezreal, he drops their win rate by -3.1% to 43.8%. This shows that there is a very bad strategic relationship between Ezreal and Nautilus that allows them to perform worse together than alone.
Nautilus has a lower difficulty than Ezreal. That means you don't need to be very careful when lining up Nautilus teammates to go into battle on the same side as, as they will have to have a lower level of skill to be able to play well with you.
Fighting cooperatively, Ezreal players will likely observe an overall large increase in your team’s ability to deal magical damage. Together, these champions can deal quite a lot of AP type damage.
In contrast, by grouping Ezreal and Nautilus together, you will not be granting your other teammates much support. Plan to pick other champs on your team that neutralizes this relative disparity in this pairing's kit.
Regardless of your Nautilus ally's ability, you should focus on increasing your income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you will do well, regardless.
If you would like to truly master Ezreal in order to work well with Nautilus during both the lane and mid / late game phases of LoL, you should keep reading to gather some more tips and tricks for this champion pairing. If you mind the build and tips displayed here, you will increase your win rate by a lot.
The most important items to focus on in your Ezreal and Nautilus synergy build include Trinity Force, Spear of Shojin, and Serylda's Grudge. When Ezreal used at least these three great items in his build, he performed a lot better when fighting alongside Nautilus than with most other common item sets. In fact, Ezreal boasted an average winrate of 43.8% when synergizing his build and playstyle to Nautilus with these items in his kit.
To have the best likelihood of coming out on top against your oponents, you should equip the Press the Attack, Presence of Mind, Legend: Bloodline, Coup de Grace, Magical Footwear, and Biscuit Delivery runes from the Precision and Inspiration rune sets. Out of all the rune sets players used for this champion pairing, this set of runes yielded the top win rate. Notably, these runes averaged a 43.8% win rate overall.
By default, tips, stats, and builds on how to pair Nautilus with Ezreal are shown for all ranked divisions. If you want to scope the statistics and builds to an individual player tier, you can use the selection menu above.