Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Elise's Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
When in Spider Form, Spiderlings will attack the target that Elise uses Venomous Bite on.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Elise Twitch synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Twitch, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Elise sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Twitch. His KDA went down from NaN to NaN. This worsening shows that Twitch helps Elise perform worse in competitive League matches. Yet, the small difference proves that this performance change is only marginal.
When Elise is paired with Twitch, she sees a small increase in her full damage output. This difference may demonstrate that Twitch helps provide protection for her to dish out more damage or that his participation also helps increase the round's duration. Similarly, when Elise is played together with Twitch on the same team, he usually scores many fewer killing sprees compared to when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Twitch.
Moreover, when Elise plays with Twitch on the same side, she on average takes a little more damage than when she plays alone. Getting dealt more damage may mean that Twitch does a poor job of covering Elise during team fights.
There is no one best synergy for Elise that will 100% of the time be her #1 synergy. However, Twitch is a good ally for Elise. By being on the same team as Elise, he raises their win rate by 1.0% to 49.1%. This shows that there is a somewhat important strategic relationship between Elise and Twitch that allows them to perform better together than alone.
Twitch has a much lower diffuclty than Elise. That means you don't need to be careful when enlisting Twitch comrades to go into battle on the same side as, as they will require a much lower level of skill to be able to cooperate well with you.
Working together, Elise players will likely observe an overall large increase in your team’s capability to dish out massive AD. Combined, these champs can provide a great amount of sustained physical damage.
Conversely, by grouping Elise and Twitch together, you will not be granting your side enough utility. Make sure to include other champs on your team that fills this relative disparity in their abilities.
Regardless of your Twitch ally's skill level, you need to focus on maximizing your income, outlasting your enemies, and taking down objectives. If you do this, you should do well, regardless.
If you would like to learn all of the intricacies of Elise to pair well with Twitch during both the laning and mid / late game phases of League of Legends, you should keep reading to master some more lessons on this champion pairing. If you listen to the build and suggestions shown here, you will grow your win rate by a lot.
The best items to prioritize in your Elise and Twitch synergy build include Rabadon's Deathcap, Shadowflame, and Stormsurge. When Elise used at least these three pieces in her build, she performed much better when paired up with Twitch than with many other common builds. In fact, Elise had an average win rate of 49.1% when playing alongside Twitch with this build.
To have the best probability of annihilating your oponents, you should take the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Nimbus Cloak, and Waterwalking runes from the Domination and Sorcery rune sets. Out of all the rune sets players used for this champion pairing, this mix of runes resulted in the best win rate. Notably, these runes provided a 49.1% win rate overall.
By default, tips, statistics, and builds on how to synergize Twitch with Elise are given for all ranked divisions. If you want to narrow the stats and builds to a particular player tier, you may use the selection menu above.