Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Elise's Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
When in Spider Form, Spiderlings will attack the target that Elise uses Venomous Bite on.
You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
The Elise Neeko synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Neeko, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Elise sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Neeko. His KDA fell from NaN to NaN. This fall shows that Neeko helps Elise perform poorer in competitive LoL rounds. Yet, the small difference proves that this performance change is not very impactful.
When Elise is an ally to Neeko, she gets a little increase in her full damage dealt. This change could demonstrate that Neeko supports by providing cover for her to deal more damage or that her support also helps increase the round's duration. Similarly, when Elise is played with Neeko on the same side, he usually scores many fewer killing sprees than when she plays on his own. This is contrasting evidence that she is worse when playing synergisticly with Neeko.
Additionally, when Elise plays with Neeko on the same side, she often receives a little more damage than when she fights alone. Receiving more damage could mean that Neeko does a poor job of protecting Elise in team fights.
There is no universally accepted best ally for Elise that will 100% of the time be her ideal synergy. Yet, Neeko is a very bad companion for Elise. By being on the same team as Elise, she decreases their win rate by -4.3% to 43.8%. This shows that there is a terrible bond between Elise and Neeko that allows them to perform worse together than alone.
Neeko has a much lower diffuclty than Elise. That means you don't need to be cautious when enlisting Neeko comrades to fight alongside, as they will require a much lower level of skill to be able to fight well with you.
When playing alongside, Elise players will likely witness an overall large increase in your team’s ability to to do a lot of AP damage. When paired, these two can blast through enemies with magic damage.
In contrast, by aligning Elise and Neeko together, you probably will not be giving your side very much protection for burst damage. Plan to bring other champs on your team that fills this hole in this pairing's kit.
Regardless of the ability of your Neeko ally, you need to focus on increasing your income, warding to avoid ambushes, and taking down objectives. If you do this, you will do well, regardless.
To truly master Elise in order to work well with Neeko during both the early game and mid / late game phases of League games, you should continue reading to learn a few extra tricks and insights into this champion pairing. If you pay attention to the build and tips displayed here, you should increase your win rate by a lot.
The most important items to focus on in your Elise and Neeko synergy build include Zhonya's Hourglass, Shadowflame, and Stormsurge. When Elise included at least these three pieces in her build, she performed significantly better when paired up with Neeko than with most other typical item sets. In fact, Elise had an average winrate of 43.8% helping carry Neeko with these items in her kit.
To have the greatest chance of annihilating your oponents, you should use the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Nimbus Cloak, and Waterwalking runes from the Domination and Sorcery rune sets. Out of all the rune combinations players chose for this champion pairing, this mix of runes yielded the top win rate. Moreover, these runes provided a 43.8% winrate overall.
By default, tips, stats, and builds on how to team up Neeko with Elise are presented for every ranked division. If you would like to filter the statistics and builds to a specific division, you may use the selection menu above.