Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Elise's Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
When in Spider Form, Spiderlings will attack the target that Elise uses Venomous Bite on.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Elise Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Elise sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This decrease shows that Karthus helps Elise perform not as well in ranked LoL rounds. Yet, the small difference proves that this performance change is not very impactful.
When Elise is paired with Karthus, she gets a small increase in her complete damage output. This change could indicate that Karthus helps provide cover for her to dish out more damage or that his presence on the team also helps extend the match's duration. Similarly, when Elise is played together with Karthus on the same team, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Karthus.
Additionally, when Elise plays with Karthus on the same team, she usually receives a little more damage than when she fights alone. Taking more damage may mean that Karthus does a poor job of covering Elise during team fights.
There is no one best companion for Elise that will no matter what be her ideal ally. However, Karthus is a very bad ally for Elise. By playing on the same side as Elise, he lowers their win rate by -3.3% to 44.8%. This demonstrates that there is a terrible bond between Elise and Karthus that allows them to perform not as well together than alone.
Karthus has a lower difficulty than Elise. That means Elise players don't need to be very careful when lining up Karthus allies to play with, as they will need a relatively low level of skill to play well with you.
When playing cooperatively, Elise players should expect to observe an overall large increase in your team’s ability to deal magic damage. Combined, these champs can deal quite a lot of AP type damage.
Conversely, by aligning Elise and Karthus together, you probably will not be granting your other allies much tankyness. We recommend you include other champions on your team that offsets this disparity in their kit.
Regardless of your Karthus ally's ability, you need to focus on increasing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you should do well anyway.
To truly master Elise in order to synergize with Karthus during both the early game and mid / late game phases of LoL matches, you should keep reading to pick up additional tricks and insights into this champion pairing. If you pay attention to the build and tips displayed here, you will increase your win rate by a lot.
The most important items to prioritize in your Elise and Karthus synergy build include Rabadon's Deathcap, Lich Bane, and Stormsurge. When Elise used at least these three pieces in her build, she did significantly better as an ally of Karthus than with many other typical item sets. In fact, Elise boasted an average winrate of 44.8% when synergizing her build and playstyle to Karthus with these items in her kit.
To have the greatest likelihood of coming out on top against your oponents, Elise players should equip the Press the Attack, Triumph, Legend: Alacrity, Coup de Grace, Eyeball Collection, and Relentless Hunter runes from the Precision and Domination rune sets. Of all the rune combinations players used for Elise and Karthus pairings, this set of runes resulted in the greatest win rate. Notably, these runes averaged a 44.8% win rate overall.
If you want to view Elise and Karthus collaboration tips and stats for a a distinct rank, please choose one from the selection menu displayed above. If viewing for the first time, the stats and build suggestions shown are calculated using all matches played with these champs.