Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Cassiopeia Vex synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Vex, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Vex. His KDA went down from NaN to NaN. This fall shows that Vex helps Cassiopeia perform worse in ranked League games. Yet, the small difference indicates that this performance change is only marginal.
When Cassiopeia tries to synergize with Vex, she observes a noticable increase in her full damage output. This may demonstrate that Vex provides cover for her to deal more damage or that their support also helps increase the round's duration. Similarly, when Cassiopeia is played together with Vex on the same team, he usually scores many fewer killing sprees compared to when she plays without Vex. This is contrasting evidence that she is worse when playing with Vex.
Moreover, when Cassiopeia plays with Vex on the same side, she usually receives more damage than when she fights alone. Taking more damage could indicate that Vex does a poor job of covering Cassiopeia in teamfights.
There is no ideal synergy for Cassiopeia that will no matter what be her ideal teammate. Yet, overall, Vex is a terrible ally for Cassiopeia. By locking into the same team as Cassiopeia, they drops their win rate by -5.5% to 44.8%. This demonstrates that there is a very bad bond between Cassiopeia and Vex that results in them performing not as well together than alone.
Vex has a much lower diffuclty than Cassiopeia. That means Cassiopeia players don't need to be cautious when arranging Vex comrades to go into battle on the same side as, as they will have to have a much lower level of skill to be able to fight well with you.
Fighting alongside, you should expect to observe an overall large increase in your team’s capability to buff allies and debuff enemies. Together, these champions may be able to carry with the power of their abilities.
In contrast, by bringing Cassiopeia and Vex together, you probably will not be giving your side enough sustained damage output. We recommend you have other champions on your team that fills this relative disparity in this pairing's kit.
Regardless of your Vex ally's ability, you should focus on increasing your gold income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you will do well, regardless.
To truly master Cassiopeia to pair well with Vex during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up additional tricks and insights into this champion pairing. If you mind the build and suggestions presented above, you will increase your win rate significantly.
The most crucial finished items to include in your Cassiopeia and Vex synergy build include Seraph's Embrace, Rylai's Crystal Scepter, and Rod of Ages. When Cassiopeia included at least these three items in her build, she performed much better when fighting alongside Vex than with many other commonly used item sets. In fact, Cassiopeia had an average winrate of 44.8% helping carry Vex with this build.
To have the highest probability of crushing your oponents, you should equip the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the runes we have analyed for Cassiopeia and Vex pairings, this mix of runes resulted in the greatest win rate. In fact, these runes gave a 44.8% winrate overall.
By default, tips, statistics, and builds on how to synergize Vex with Cassiopeia are given for all skill levels combined. To narrow the statistics and builds to a specific rank, you should use the selection menu located above.