Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Cassiopeia Twitch synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Twitch, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Twitch. His KDA went down from NaN to NaN. This decrease shows that Twitch helps Cassiopeia perform not as well in ranked LoL matches. Yet, the small difference proves that this performance change is not very impactful.
When Cassiopeia plays on the same team as Twitch, she observes a little increase in her complete damage dealt. This change may signal that Twitch supports by providing protection for her to dish out more damage or that his presence also helps extend the match's duration. Similarly, when Cassiopeia is played together with Twitch on the same side, he usually scores many fewer killing sprees compared to when she plays without Twitch. This is contrasting evidence that she is worse when playing with Twitch.
Moreover, when Cassiopeia plays with Twitch on the same team, she often receives a little more damage than when she plays alone. Receiving more damage could mean that Twitch does a poor job of covering Cassiopeia during team fights.
There is no perfect champion pairing for Cassiopeia that will always be her #1 synergy. However, overall, Twitch is a decent ally for Cassiopeia. By being on the same side as Cassiopeia, he raises their win rate by 2.2% to 52.5%. This signals that there is a good strategic relationship between Cassiopeia and Twitch that allows them to perform at the top of their game together than alone.
Twitch has a much lower diffuclty than Cassiopeia. That means you don't need to be careful when enlisting Twitch teammates to fight alongside, as they will have to have a much lower level of skill to work well with you.
Working on the same side, you will likely see an overall large increase in your team’s ability to deal magic damage. When paired, these champs can blast through enemies with magic damage.
Although, by aligning Cassiopeia and Twitch together, you will not be giving your team a great deal of engage. We recommend you have other champs on your team that offsets this hole in their potential.
Regardless of the ability of your Twitch teammate, you should focus on maximizing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you should do well, regardless.
To learn all of the intricacies of Cassiopeia in order to work well with Twitch during both the lane and mid / late game phases of League of Legends rounds, you should keep reading to master some more tips and tricks for this champion pairing. If you use the build and tips presented here, you should grow your win rate significantly.
The best items to use in your Cassiopeia and Twitch synergy build consist of Seraph's Embrace, Cosmic Drive, and Rod of Ages. When Cassiopeia used at least these three items in her build, she performed significantly better as an ally of Twitch than with most other commonly used builds. In fact, Cassiopeia had an average winrate of 52.5% when synergizing her build and playstyle to Twitch with these items in her kit.
To have the highest probability of crushing your oponents, Cassiopeia players should take the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the rune builds that we analyzed for this champion pairing, this sequence of runes resulted in the top win rate. Notably, these runes provided a 52.5% win rate overall.
By default, tips, stats, and builds on how to team up Twitch with Cassiopeia are given for every ranked division. If you would like to scope the stats and builds to a specific rank, you may use the selection menu earlier on the page.