Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
To maximize your ultimate's damage use it when there are many spheres on the battlefield.
After you hit an enemy champion with Force of Will follow up with Dark Sphere, they'll be slowed and have a hard time avoiding it.
Get one of your spells to rank 5 as quickly as possible, they gain powerful bonus effects at max rank.
The Cassiopeia Syndra synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Syndra, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Syndra. His KDA decreased from NaN to NaN. This worsening shows that Syndra helps Cassiopeia perform not as well in competitive League of Legends games. Yet, the small difference indicates that this performance change is not very impactful.
When Cassiopeia tries to synergize with Syndra, she sees a measurable drop in her full damage dealt. This difference may demonstrate that Syndra does not support by providing cover for her to dish out more damage or that her participation also helps extend the match's duration. Similarly, when Cassiopeia is played alongside Syndra on the same side, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing alongside Syndra.
Moreover, when Cassiopeia plays with Syndra on the same team, she often takes a little less damage than when she fights alone. Taking not as much damage may mean that Syndra does a decent job of covering Cassiopeia during team fights.
There is no top champion pairing for Cassiopeia that will 100% of the time be her ideal teammate. However, overall, Syndra is a very bad teammate for Cassiopeia. By being on the same side as Cassiopeia, she decreases their win rate by -5.6% to 44.7%. This shows that there is a very bad strategic relationship between Cassiopeia and Syndra that results in them performing not as well together than without each other.
Syndra has a lower difficulty than Cassiopeia. That means you don't need to be cautious when enlisting Syndra comrades to fight alongside, as they will require a relatively low level of skill to be able to do well with you.
When playing cooperatively, Cassiopeia players should expect to see an overall large increase in your team’s capacity to deal magical damage. Together, these champions are able to dish out a surprising amount of magic type damage.
In contrast, by grouping Cassiopeia and Syndra together, you probably will not be granting your other teammates a great deal of anti-tank damage dealing potential. We recommend you have other champions on your team that neutralizes this hole in their abilities.
Regardless of your Syndra ally's skill level, you should focus on increasing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Cassiopeia in order to pair well with Syndra during both the laning and mid / late game phases of LoL matches, you should keep reading to pick up additional lessons on this champion pairing. If you pay attention to the build and tips displayed here, you should increase your win rate significantly.
The top finished items to use in your Cassiopeia and Syndra synergy build include Seraph's Embrace, Rylai's Crystal Scepter, and Rod of Ages. When Cassiopeia incorporated at least these three great items in her build, she performed significantly better when paired up with Syndra than with many other commonly used item sets. In fact, Cassiopeia had an average win rate of 44.7% when synergizing her build and playstyle to Syndra with this build.
To have the best chance of vanquishing your oponents, you should take the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the rune sets players used for this champion pairing, this combination of runes resulted in the greatest win rate. In fact, these runes gave a 44.7% win rate overall.
If you need to get Cassiopeia and Syndra cooperations tips and builds for a a particular division rank, feel free to choose one from the selection menu provided above. If viewing for the first time, the stats and tips and suggestions displayed are calculated using all games with data with both champs.