Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Cassiopeia Seraphine synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Seraphine, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Seraphine. His KDA went down from NaN to NaN. This drop shows that Seraphine helps Cassiopeia perform poorer in ranked LoL games. Yet, the small difference proves that this performance change is only marginal.
When Cassiopeia tries to synergize with Seraphine, she observes a small increase in her total damage output. This change may signal that Seraphine provides cover for her to deal more damage or that her presence on the team also helps increase the game's duration. Similarly, when Cassiopeia is played alongside Seraphine on the same team, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing with Seraphine.
Moreover, when Cassiopeia plays with Seraphine on the same team, she often takes a little more damage than when she plays alone. Getting dealt more damage could indicate that Seraphine does a poor job of covering Cassiopeia during teamfights.
There is no one best ally for Cassiopeia that will no matter what be her #1 teammate. Yet, overall, Seraphine is a very typical teammate for Cassiopeia. By being on the same side as Cassiopeia, she has no effect on their win rate by 0.0% to 50.3%. This proves that there is not really a strong synergy between Cassiopeia and Seraphine that results in them performing at the same level together than without each other.
Seraphine has a much lower diffuclty than Cassiopeia. That means you don't need to be cautious when enlisting Seraphine teammates to fight alongside, as they will need a much lower level of skill to work well with you.
Working alongside, Cassiopeia players should witness an overall large increase in your team’s capability to provide utility and CC for your side. Together, these champions will help their other teammates secure a victory.
Although, by grouping Cassiopeia and Seraphine together, you may not be granting your team enough attack damage. Make sure to pick other champions on your team that nullifies this gap in this pairing's capabilities.
Regardless of your Seraphine ally's ability, you need to focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you follow these simple suggestions, you will do well, regardless.
To learn all of the intricacies of Cassiopeia in order to pair well with Seraphine during both the early game and mid / late game phases of LoL rounds, you should continue reading to pick up some more tips and tricks for this champion pairing. If you use the build and suggestions displayed here, you should increase your win rate by a lot.
The most important finished items to focus on in your Cassiopeia and Seraphine synergy build include Seraph's Embrace, Cosmic Drive, and Rod of Ages. When Cassiopeia combined at least these three pieces in her build, she performed much better when fighting alongside Seraphine than with many other common builds. In fact, Cassiopeia had an average winrate of 50.3% when synergizing her build and playstyle to Seraphine with this build.
To have the greatest chance of annihilating your oponents, Cassiopeia players should equip the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Of all the rune builds players picked for Cassiopeia and Seraphine pairings, this order of runes resulted in the greatest win rate. Notably, these runes gave a 50.3% winrate overall.
If you would like to see Cassiopeia with Seraphine collaboration tips and builds for a a particular division rank, please choose one from the selection menu provided above. By default, the statistics and strategies displayed are computed using all games played with both champions.