Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Use Overload's passive to optimize for maximum damage or maximum speed.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.
The Cassiopeia Ryze synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Ryze, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Ryze. His KDA fell from NaN to NaN. This fall shows that Ryze helps Cassiopeia perform worse in competitive LoL matches. Yet, the small difference indicates that this performance change is only marginal.
When Cassiopeia plays on the same team as Ryze, she gets a marginal improvement in her total damage dealt. This change may demonstrate that Ryze helps provide protection for her to deal more damage or that his allyship also helps increase the game's duration. Similarly, when Cassiopeia is played together with Ryze on the same team, he usually scores many fewer killing sprees than when she plays without Ryze. This is contrasting evidence that she is worse when playing synergisticly with Ryze.
Additionally, when Cassiopeia plays with Ryze on the same team, she often receives more damage than when she fights alone. Receiving more damage may indicate that Ryze does a poor job of covering Cassiopeia during team fights.
There is no perfect champion pairing for Cassiopeia that will always be her best synergy. However, overall, Ryze is a terrible ally for Cassiopeia. By being on the same team as Cassiopeia, he decreases their win rate by -6.2% to 44.1%. This shows that there is a very bad strategic relationship between Cassiopeia and Ryze that allows them to perform worse together than without each other.
Ryze has a much lower diffuclty than Cassiopeia. That means Cassiopeia players don't need to be careful when finding Ryze comrades to fight alongside, as they will require a much lower level of skill to do well with you.
When playing cooperatively, Cassiopeia players should see an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these two can deal quite a lot of AP type damage.
In contrast, by pairing Cassiopeia and Ryze together, you will not be giving your team a lot of AD. Make sure to pick other champions on your team that neutralizes this relative hole in their potential.
Regardless of the skill of your Ryze teammate, you should focus on increasing your gold income, warding to avoid ambushes, and taking down objectives. If you follow these simple suggestions, you should do well anyway.
To truly master Cassiopeia in order to pair well with Ryze during both the laning and mid / late game phases of League rounds, you should keep reading to pick up some more tips and tricks for this champion pairing. If you listen to the build and suggestions presented above, you will grow your win rate by a lot.
The most crucial finished items to use in your Cassiopeia and Ryze synergy build include Seraph's Embrace, Rylai's Crystal Scepter, and Rod of Ages. When Cassiopeia incorporated at least these three items in her build, she did much better as an ally of Ryze than with most other common builds. In fact, Cassiopeia had an average win rate of 44.1% when synergizing her build and playstyle to Ryze with these items in her kit.
To have the highest probability of beating your oponents, Cassiopeia players should equip the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Of all the rune builds players picked for this champion pairing, this combination of runes yielded the best win rate. Moreover, these runes averaged a 44.1% win rate overall.
If you need to view Cassiopeia and Ryze synergy tips and stats for a a specific rank, feel free to select one from the selection menu provided above. At first, the statistics and tips and suggestions displayed are calculated using all matches played with these champions.