Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Keeping tunnels spread out across the map will ensure you have choices when you want to cast Void Rush.
Cast Burrow before travelling around the map to take advantage of the increased Move Speed and the safety provided by Tremor Sense.
Tremor Sense can warn you of enemies closing in, and is particularly useful when entering enemy territory.
The Cassiopeia Rek'Sai synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Rek'Sai, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Rek'Sai. His KDA decreased from NaN to NaN. This fall shows that Rek'Sai helps Cassiopeia perform not as well in ranked League of Legends games. Yet, the small difference shows that this performance change is not very impactful.
When Cassiopeia tries to synergize with Rek'Sai, she sees a little drop in her total damage dealt. This may signal that Rek'Sai does not help cover for her to dish out more damage or that his participation also helps increase the game's duration. Similarly, when Cassiopeia is played alongside Rek'Sai on the same side, he usually scores many fewer killing sprees than when she plays without Rek'Sai. This is contrasting evidence that she is worse when playing synergisticly with Rek'Sai.
Additionally, when Cassiopeia plays with Rek'Sai on the same team, she often receives a little less damage than when she fights alone. Receiving not as much damage could mean that Rek'Sai does a decent job of protecting Cassiopeia during team fights.
There is no one best synergy for Cassiopeia that will always be her top ally. However, Rek'Sai is a very typical teammate for Cassiopeia. By playing on the same side as Cassiopeia, he drops their win rate by -1.0% to 49.3%. This proves that there is only a small strategic relationship between Cassiopeia and Rek'Sai that allows them to perform worse together than alone.
Rek'Sai has a much lower diffuclty than Cassiopeia. That means you don't need to be cautious when arranging Rek'Sai allies to go into battle on the same side as, as they will need a much lower level of skill to be able to cooperate well with you.
Fighting on the same side, Cassiopeia players will likely observe an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these champs can deal quite a lot of AP type damage.
Although, by bringing Cassiopeia and Rek'Sai together, you may not be providing your other allies a lot of engage potential. Make sure to include other champions on your team that nullifies this gap in their abilities.
Regardless of the skill of your Rek'Sai ally, you should focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you do this, you will do well, regardless.
To truly master Cassiopeia to work well with Rek'Sai during both the laning and mid / late game phases of League of Legends rounds, you should continue reading to pick up a few extra tricks and insights into this champion pairing. If you listen to the build and stats shown here, you will grow your win rate significantly.
The most important finished items to have in your Cassiopeia and Rek'Sai synergy build include Seraph's Embrace, Rylai's Crystal Scepter, and Rod of Ages. When Cassiopeia used at least these three great items in her build, she did significantly better as an ally of Rek'Sai than with many other commonly used builds. In fact, Cassiopeia had an average win rate of 49.3% when synergizing her build and playstyle to Rek'Sai with this build.
To have the best likelihood of defeating your oponents, Cassiopeia players should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the rune sets players picked for this champion pairing, this composite of runes yielded the greatest win rate. In fact, these runes averaged a 49.3% win rate overall.
If you want to see Cassiopeia with Rek'Sai synergy tips and stats for a an individual skill level, feel free to select one from the selection menu shown above. If viewing for the first time, the statistics and build suggestions displayed are calculated using all matches finished with both champs.