Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
While ganking, consider aiming Dredge Line at nearby terrain and following it up with Riptide for a higher hit rate.
Riptide has a delayed blast timing on activation - you can use this while running away or when enemies are incoming to serve as a deterrent.
The Cassiopeia Nautilus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Nautilus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Nautilus. His KDA fell from NaN to NaN. This decrease shows that Nautilus helps Cassiopeia perform worse in ranked League of Legends matches. Yet, the small difference indicates that this performance change is not very impactful.
When Cassiopeia tries to synergize with Nautilus, she sees a little increase in her total damage output. This could demonstrate that Nautilus provides protection for her to deal more damage or that his support also helps increase the round's duration. Similarly, when Cassiopeia is played with Nautilus on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing alongside Nautilus.
Moreover, when Cassiopeia plays with Nautilus on the same side, she often receives a little less damage than when she plays alone. Taking not as much damage could mean that Nautilus does a decent job of protecting Cassiopeia in teamfights.
There is no universally accepted best companion for Cassiopeia that will 100% of the time be her best synergy. However, Nautilus is a not very good teammate for Cassiopeia. By being on the same team as Cassiopeia, he drops their win rate by -1.7% to 48.6%. This clearly indicates that there is a harmful bond between Cassiopeia and Nautilus that allows them to perform not as well together than without each other.
Nautilus has a much lower diffuclty than Cassiopeia. That means you don't need to be very careful when enlisting Nautilus teammates to go into battle on the same side as, as they will have to have a much lower level of skill to be able to play well with you.
Fighting cooperatively, you will likely see an overall large increase in your team’s ability to deal magic damage. Combined, these two can deal quite a lot of AP type damage.
In contrast, by grouping Cassiopeia and Nautilus together, you will not be providing your team enough sustained damage output. We recommend you pick other champs on your team that nullifies this gap in this pairing's kit.
Regardless of the ability of your Nautilus ally, you need to focus on increasing your income, staying alive by avoiding foolish fights, and clearing objectives. If you follow these simple suggestions, you will do well, regardless.
If you would like to learn all of the intricacies of Cassiopeia to pair well with Nautilus during both the early game and mid / late game phases of League, you should keep reading to gather a few extra lessons on this champion pairing. If you mind the build and tips presented here, you will increase your win rate significantly.
The most crucial items to have in your Cassiopeia and Nautilus synergy build consist of Seraph's Embrace, Cosmic Drive, and Rod of Ages. When Cassiopeia combined at least these three finished items in her build, she performed significantly better as an ally of Nautilus than with most other commonly used builds. In fact, Cassiopeia boasted an average winrate of 48.6% when synergizing her build and playstyle to Nautilus with this build.
To have the greatest likelihood of annihilating your oponents, you should take the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the rune builds we have analyed for this champion pairing, this order of runes yielded the best win rate. Notably, these runes provided a 48.6% winrate overall.
If you would like to see Cassiopeia and Nautilus synergy tips and stats for a a particular division rank, please select one from the selection menu above. If viewing for the first time, the statistics and strategies displayed are computed using every match finished with these champions.