Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Kayle benefits greatly from Attack Damage and Ability Power, making hybrid items like Nashor's Tooth and Hextech Gunblade very effective on her.
Using Divine Judgment on a high-DPS ally can turn the tides of battle by giving your ally free reign to attack.
Kayle's attacks become incredibly powerful once she gains attack range from Divine Ascent. Play safe until then.
The Cassiopeia Kayle synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Kayle, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Kayle. His KDA went down from NaN to NaN. This drop shows that Kayle helps Cassiopeia perform not as well in competitive League of Legends matches. Yet, the small difference shows that this performance change is only marginal.
When Cassiopeia is an ally to Kayle, she observes a marginal improvement in her total damage output. This difference may demonstrate that Kayle helps provide cover for her to deal more damage or that her support also helps increase the round's duration. Similarly, when Cassiopeia is played with Kayle on the same team, he usually scores many fewer killing sprees than when she plays on his own. This is contrasting evidence that she is worse when playing alongside Kayle.
Additionally, when Cassiopeia plays with Kayle on the same team, she typically receives a little more damage than when she plays alone. Getting dealt more damage could mean that Kayle does a poor job of protecting Cassiopeia in teamfights.
There is no ideal champion pairing for Cassiopeia that will no matter what be her ideal ally. However, Kayle is a pretty good teammate for Cassiopeia. By playing on the same side as Cassiopeia, she improves their win rate by 1.2% to 51.5%. This signals that there is a potentially meaningful synergy between Cassiopeia and Kayle that allows them to perform stronger together than without each other.
Kayle has a much lower diffuclty than Cassiopeia. That means Cassiopeia players don't need to be careful when finding Kayle teammates to go into battle on the same side as, as they will require a much lower level of skill to be able to do well with you.
Working together, Cassiopeia players should observe an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these champs can deal quite a lot of AP type damage.
In contrast, by aligning Cassiopeia and Kayle together, you probably will not be providing your other allies enough anti-tank damage dealing potential. Plan to include other champs on your team that offsets this hole in this pairing's potential.
Regardless of the skill of your Kayle ally, you need to focus on increasing your income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you will do well anyway.
If you would like to truly master Cassiopeia in order to pair well with Kayle during both the laning and mid / late game phases of League of Legends, you should continue reading to master a few extra tricks and insights into this champion pairing. If you pay attention to the build and tips presented here, you will increase your win rate significantly.
The best finished items to prioritize in your Cassiopeia and Kayle synergy build include Seraph's Embrace, Rylai's Crystal Scepter, and Cosmic Drive. When Cassiopeia used at least these three pieces in her build, she did significantly better when paired up with Kayle than with many other commonly used item sets. In fact, Cassiopeia had an average win rate of 51.5% when playing alongside Kayle with this build.
To have the highest probability of vanquishing your oponents, Cassiopeia players should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the rune sets players used for Cassiopeia and Kayle pairings, this blending of runes resulted in the greatest win rate. Notably, these runes provided a 51.5% winrate overall.
If you would like to view Cassiopeia with Kayle synergy tips and builds for a a specific player tier, feel free to choose one from the selection menu shown above. By default, the statistics and build suggestions shown are computed using all rounds run with both champions.