Use the CC from your abilities to land both of your Precision Protocol attacks on enemies.
Try waiting until the other team is distracted with fighting your team, and use Hookshot to pick off vulnerable targets.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Camille Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Camille sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This decrease shows that Karthus helps Camille perform worse in competitive League of Legends rounds. Yet, the small difference indicates that this performance change is only marginal.
When Camille plays on the same team as Karthus, she sees a marginal improvement in her full damage dealt. This may signal that Karthus helps provide cover for her to deal more damage or that his presence also helps extend the round's duration. Similarly, when Camille is played with Karthus on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing synergisticly with Karthus.
Additionally, when Camille plays with Karthus on the same side, she usually receives more damage than when she plays alone. Getting dealt more damage could indicate that Karthus does a poor job of covering Camille during teamfights.
There is no ideal champion pairing for Camille that will no matter what be her #1 ally. Yet, overall, Karthus is a relatively poor ally for Camille. By being on the same team as Camille, he drops their win rate by -2.2% to 46.4%. This demonstrates that there is a bad synergy between Camille and Karthus that allows them to perform not as well together than without each other.
Karthus has a greater difficulty than Camille. That means Camille players need to be cautious when lining up Karthus teammates to fight alongside, as they will require a greater level of skill to cooperate well with you.
When playing together, Camille players should expect to witness an overall large increase in your team’s capability to to do a lot of AP damage. Together, these champs can deal quite a lot of AP type damage.
Although, by grouping Camille and Karthus together, you will not be giving your other allies much utility. Make sure to have other champions on your team that helps cover this gap in this pairing's potential.
Regardless of your Karthus ally's skill level, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you follow these simple suggestions, you should do well anyway.
If you would like to learn all of the intricacies of Camille to synergize with Karthus during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tips and tricks for this champion pairing. If you pay attention to the build and tips presented above, you will increase your win rate by a lot.
The most important items to include in your Camille and Karthus synergy build consist of Sterak's Gage, Ravenous Hydra, and Trinity Force. When Camille incorporated at least these three finished items in her build, she performed much better when paired up with Karthus than with many other commonly used item sets. In fact, Camille had an average win rate of 46.4% when playing alongside Karthus with this build.
To have the best likelihood of crushing your oponents, you should take the Grasp of the Undying, Shield Bash, Bone Plating, Unflinching, Biscuit Delivery, and Magical Footwear runes from the Resolve and Inspiration rune sets. Out of all the runes we have analyed for this team composition, this combination of runes yielded the highest win rate. Notably, these runes gave a 46.4% win rate overall.
By default, tips, statistics, and builds on how to team up Karthus with Camille are given for every ranked division. If you would like to narrow the statistics and builds to a particular rank, you should use the selection menu earlier in the counter matchup guide.