Each of Aphelios' weapons have different strengths, so try to find the right situation for your current weapons.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Aphelios Karthus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Karthus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Aphelios sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA decreased from NaN to NaN. This worsening shows that Karthus helps Aphelios perform poorer in ranked League of Legends matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Aphelios is an ally to Karthus, he observes a marginal improvement in his complete damage output. This difference could indicate that Karthus helps provide cover for him to dish out more damage or that his allyship also helps extend the match's duration. Similarly, when Aphelios is played together with Karthus on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing alongside Karthus.
Moreover, when Aphelios plays with Karthus on the same team, he often takes a little more damage than when he fights alone. Receiving more damage could indicate that Karthus does a poor job of protecting Aphelios in teamfights.
There is no one best synergy for Aphelios that will 100% of the time be his top ally. Yet, Karthus is a below average teammate for Aphelios. By locking into the same team as Aphelios, he drops their win rate by -1.6% to 47.0%. This signals that there is a harmful bond between Aphelios and Karthus that allows them to perform worse together than without each other.
Karthus has a much lower diffuclty than Aphelios. That means Aphelios players don't need to be careful when arranging Karthus comrades to go into battle on the same side as, as they will require a much lower level of skill to be able to work well with you.
Working cooperatively, Aphelios players should see an overall large increase in your team’s ability to deal magical damage. Together, these champs can deal quite a lot of AP type damage.
Although, by bringing Aphelios and Karthus together, you will not be providing your other teammates very much tankyness. Plan to include other champs on your team that offsets this hole in their potential.
Regardless of your Karthus ally's skill level, you need to focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you should do well anyway.
To learn all of the intricacies of Aphelios in order to synergize with Karthus during both the early game and mid / late game phases of League of Legends matches, you should keep reading to gather some more lessons on this champion pairing. If you pay attention to the build and stats displayed above, you should increase your win rate by a lot.
The best items to include in your Aphelios and Karthus synergy build include Infinity Edge, Bloodthirster, and Stormrazor. When Aphelios combined at least these three items in his build, he performed much better when paired up with Karthus than with most other commonly used item sets. In fact, Aphelios had an average win rate of 47.0% helping carry Karthus with these items in his kit.
To have the greatest likelihood of defeating your oponents, Aphelios players should use the Lethal Tempo, Overheal, Legend: Bloodline, Cut Down, Absolute Focus, and Gathering Storm runes from the Precision and Sorcery rune sets. Of all the rune sets players chose for this champion pairing, this sequence of runes yielded the best win rate. In fact, these runes averaged a 47.0% winrate overall.
By default, tips, stats, and builds on how to synergize Karthus with Aphelios are displayed for all ranked divisions. If you would like to filter the statistics and builds to an individual rank, you may use the selection menu located at the top of this page.