Each of Aphelios' weapons have different strengths, so try to find the right situation for your current weapons.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Aphelios Cassiopeia synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Cassiopeia, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Aphelios sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Cassiopeia. His KDA worsened from NaN to NaN. This worsening shows that Cassiopeia helps Aphelios perform not as well in competitive LoL rounds. Yet, the small difference proves that this performance change is not very impactful.
When Aphelios plays on the same team as Cassiopeia, he gets a little increase in his full damage output. This difference may indicate that Cassiopeia provides protection for him to dish out more damage or that her support also helps extend the round's duration. Similarly, when Aphelios is played alongside Cassiopeia on the same side, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing synergisticly with Cassiopeia.
Additionally, when Aphelios plays with Cassiopeia on the same side, he typically takes a little less damage than when he fights alone. Taking not as much damage could indicate that Cassiopeia does a decent job of protecting Aphelios in teamfights.
There is no one best ally for Aphelios that will no matter what be his ideal ally. Yet, Cassiopeia is a very typical teammate for Aphelios. By locking into the same side as Aphelios, she improves their win rate by 0.6% to 49.2%. This signals that there is not really a strong synergy between Aphelios and Cassiopeia that allows them to perform better together than alone.
Cassiopeia has a lower difficulty than Aphelios. That means Aphelios players don't need to be cautious when lining up Cassiopeia allies to fight alongside, as they will need a lower level of skill to play well with you.
Playing alongside, Aphelios players should witness an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these champions can blast through enemies with magic damage.
In contrast, by pairing Aphelios and Cassiopeia together, you probably will not be providing your other allies much engage potential. Make sure to pick other champs on your team that fills this relative gap in this pairing's potential.
Regardless of your Cassiopeia ally's skill level, you need to focus on increasing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you should do well, regardless.
If you would like to learn all of the intricacies of Aphelios to synergize with Cassiopeia during both the lane and mid / late game phases of LoL games, you should continue reading to pick up additional tips and tricks for this champion pairing. If you mind the build and stats presented above, you will increase your win rate by a lot.
The top finished items to have in your Aphelios and Cassiopeia synergy build include Infinity Edge, Bloodthirster, and Stormrazor. When Aphelios combined at least these three pieces in his build, he did significantly better as an ally of Cassiopeia than with most other commonly used builds. In fact, Aphelios boasted an average win rate of 49.2% when playing alongside Cassiopeia with these items in his kit.
To have the best chance of vanquishing your oponents, you should equip the Fleet Footwork, Overheal, Legend: Bloodline, Cut Down, Absolute Focus, and Gathering Storm runes from the Precision and Sorcery rune sets. Of all the rune sets that we analyzed for Aphelios and Cassiopeia pairings, this mixture of runes resulted in the best win rate. Moreover, these runes provided a 49.2% winrate overall.
If you would like to see Aphelios and Cassiopeia cooperations tips and stats for a an individual division, feel free to choose one from the selection menu provided above. If viewing for the first time, the statistics and guides given are computed using every game with data with both champs.