Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Annie Twitch synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Twitch, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Annie sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Twitch. His KDA decreased from NaN to NaN. This decrease shows that Twitch helps Annie perform worse in competitive LoL matches. Yet, the small difference proves that this performance change is only marginal.
When Annie is an ally to Twitch, she sees a little drop in her total damage output. This may signal that Twitch does not provide cover for her to deal more damage or that his support also helps extend the round's duration. Similarly, when Annie is played with Twitch on the same side, he usually scores many fewer killing sprees compared to when she plays without Twitch. This is contrasting evidence that she is worse when playing alongside Twitch.
Additionally, when Annie plays with Twitch on the same side, she on average receives a little more damage than when she fights alone. Taking more damage may mean that Twitch does a poor job of covering Annie during team fights.
There is no universally accepted best ally for Annie that will no matter what be her top synergy. However, Twitch is a very typical ally for Annie. By being on the same team as Annie, he raises their win rate by 0.1% to 49.4%. This shows that there is not really a strong bond between Annie and Twitch that results in them performing at the top of their game together than without each other.
Twitch has a lower difficulty than Annie. That means you don't need to be very careful when arranging Twitch comrades to play with, as they will have to have a relatively low level of skill to be able to cooperate well with you.
When playing on the same side, Annie players should observe an overall large increase in your team’s capacity to deal magic damage. Together, these champions can deal quite a lot of AP type damage.
Although, by pairing Annie and Twitch together, you will not be giving your other allies a lot of cover. Make sure to bring other champions on your team that nullifies this relative disparity in this pairing's abilities.
Regardless of your Twitch ally's skill level, you should focus on maximizing your income, warding to avoid ambushes, and clearing objectives. If you follow these simple suggestions, you will do well anyway.
To learn all of the intricacies of Annie to pair well with Twitch during both the early game and mid / late game phases of League matches, you should keep reading to pick up some more tricks and insights into this champion pairing. If you pay attention to the build and tips presented above, you will increase your win rate by a lot.
The ideal finished items to have in your Annie and Twitch synergy build include Rabadon's Deathcap, Malignance, and Stormsurge. When Annie combined at least these three great items in her build, she did much better when fighting alongside Twitch than with most other commonly used builds. In fact, Annie had an average winrate of 49.4% helping carry Twitch with these items in her kit.
To have the best probability of vanquishing your oponents, you should take the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Manaflow Band, and Absolute Focus runes from the Domination and Sorcery rune sets. Of all the rune builds that we analyzed for Annie and Twitch pairings, this combo of runes yielded the best win rate. Moreover, these runes gave a 49.4% win rate overall.
By default, tips, statistics, and builds on how to pair Twitch with Annie are given for all ranked divisions. If you want to narrow the statistics and builds to a distinct division, you should use the selection menu at the top of this page.