Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Lissandra's abilities are shorter range than those of many mages. As a result, buying items that offer both ability power and defense, like Zhonya's Hourglass and Banshee's Veil, can be a great choice to help her both survive and deal damage.
Casting Glacial Path and then running in the opposite direction will leave your enemies uncertain which way you will actually go.
You can instantly use your ultimate on yourself by pressing the self cast key and the ultimate key at once (alt+R by default).
The Annie Lissandra synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Lissandra, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Annie sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Lissandra. His KDA fell from NaN to NaN. This fall shows that Lissandra helps Annie perform worse in competitive League of Legends rounds. Yet, the small difference demonstrates that this performance change is only marginal.
When Annie is an ally to Lissandra, she sees a pretty big loss in her complete damage output. This may signal that Lissandra doesn't help cover for her to deal more damage or that her presence on the team also helps extend the round's duration. Similarly, when Annie is played alongside Lissandra on the same team, he usually scores many fewer killing sprees compared to when she plays alone. This is contrasting evidence that she is worse when playing with Lissandra.
Moreover, when Annie plays with Lissandra on the same team, she typically takes less damage than when she fights alone. Getting dealt not as much damage could mean that Lissandra does a decent job of protecting Annie in team fights.
There is no one best ally for Annie that will always be her top teammate. Yet, overall, Lissandra is a terrible ally for Annie. By being on the same team as Annie, she drops their win rate by -5.5% to 43.8%. This shows that there is an easy to overcome and exploit synergy between Annie and Lissandra that results in them performing worse together than without each other.
Lissandra has a lower difficulty than Annie. That means Annie players don't need to be cautious when enlisting Lissandra comrades to play with, as they will have to have a relatively low level of skill to cooperate well with you.
Working alongside, you will likely witness an overall large increase in your team’s capability to deal magical damage. Together, these two are able to dish out a surprising amount of magic type damage.
Conversely, by grouping Annie and Lissandra together, you will not be providing your team very much anti-tank damage dealing potential. Plan to bring other champions on your team that offsets this relative disparity in their abilities.
Regardless of the ability of your Lissandra ally, you need to focus on maximizing your gold income, warding to avoid ambushes, and taking down objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Annie in order to pair well with Lissandra during both the lane and mid / late game phases of League rounds, you should keep reading to master a few extra tricks and insights into this champion pairing. If you pay attention to the build and tips displayed above, you will increase your win rate by a lot.
The most crucial items to build first in your Annie and Lissandra synergy build include Rabadon's Deathcap, Malignance, and Liandry's Torment. When Annie bought at least these three finished items in her build, she performed significantly better as an ally of Lissandra than with most other common builds. In fact, Annie had an average win rate of 43.8% when synergizing her build and playstyle to Lissandra with these items in her kit.
To have the greatest chance of crushing your oponents, Annie players should use the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Absolute Focus, and Manaflow Band runes from the Domination and Sorcery rune sets. Of all the rune sets players used for Annie and Lissandra pairings, this combo of runes yielded the top win rate. Moreover, these runes provided a 43.8% win rate overall.
If you want to view Annie with Lissandra synergy tips and stats for a a particular skill level, feel free to select one from the selection menu above. At first, the statistics and tips and suggestions shown are calculated using every round run with both champions.