Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Take advantage of Flurry by weaving in basic attacks between spell casts - this maximizes damage output and minimizes Energy loss.
Self-casting Safeguard and using Iron Will are powerful tools for killing neutral monsters (in the jungle).
Use Sonic Wave before Dragon's Rage so you can chase the target with Resonating Strike.
The Annie Lee Sin synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Lee Sin, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Annie sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Lee Sin. His KDA decreased from NaN to NaN. This worsening shows that Lee Sin helps Annie perform poorer in competitive League of Legends matches. Yet, the small difference shows that this performance change is only marginal.
When Annie is an ally to Lee Sin, she observes a small increase in her full damage output. This change may indicate that Lee Sin helps provide cover for her to dish out more damage or that his support also helps extend the round's duration. Similarly, when Annie is played with Lee Sin on the same team, he usually scores many fewer killing sprees than when she plays without Lee Sin. This is contrasting evidence that she is worse when playing alongside Lee Sin.
Additionally, when Annie plays with Lee Sin on the same team, she typically takes a little less damage than when she fights alone. Getting dealt not as much damage may mean that Lee Sin does a decent job of covering Annie in team fights.
There is no universally accepted best ally for Annie that will 100% of the time be her #1 teammate. Yet, Lee Sin is a relatively poor ally for Annie. By locking into the same side as Annie, he decreases their win rate by -2.0% to 47.3%. This signals that there is a bad bond between Annie and Lee Sin that results in them performing not as well together than alone.
Lee Sin has a lower difficulty than Annie. That means you don't need to be very careful when finding Lee Sin teammates to fight alongside, as they will require a relatively low level of skill to work well with you.
Fighting together, you will likely witness an overall large increase in your team’s capability to deal magic damage. Together, these two can deal quite a lot of AP type damage.
Although, by pairing Annie and Lee Sin together, you will not be granting your other teammates very much tankyness. Make sure to pick other champions on your team that offsets this disparity in this pairing's capabilities.
Regardless of the skill of your Lee Sin teammate, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you will do well, regardless.
To truly master Annie to work well with Lee Sin during both the early game and mid / late game phases of LoL games, you should keep reading to pick up some more tricks and insights into this champion pairing. If you use the build and tips shown here, you will grow your win rate by a lot.
The most important finished items to include in your Annie and Lee Sin synergy build consist of Rabadon's Deathcap, Malignance, and Shadowflame. When Annie used at least these three pieces in her build, she performed much better when fighting alongside Lee Sin than with most other commonly used item sets. In fact, Annie boasted an average winrate of 47.3% when synergizing her build and playstyle to Lee Sin with these items in her kit.
To have the highest probability of defeating your oponents, Annie players should take the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Absolute Focus, and Manaflow Band runes from the Domination and Sorcery rune sets. Of all the rune sets players used for Annie and Lee Sin pairings, this blending of runes resulted in the greatest win rate. Notably, these runes averaged a 47.3% win rate overall.
By default, tips, stats, and builds on how to pair Lee Sin with Annie are shown for every ranked division. If you would like to scope the statistics and builds to a particular player tier, you may use the selection menu above.