Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Enemies are considered isolated if they have no allies within a short distance. The damage of Taste Their Fear is massively increased against these targets.
Unseen Threat activates when Kha'Zix cannot be seen by the enemy team. Reactivate by using brush or Void Assault. Don't forget to apply Unseen Threat by autoattacking enemy champions.
Kha'Zix has a great deal of freedom to choose where and when to fight. Pick your battles carefully to succeed.
The Annie Kha'Zix synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Kha'Zix, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Annie sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Kha'Zix. His KDA fell from NaN to NaN. This drop shows that Kha'Zix helps Annie perform worse in ranked League rounds. Yet, the small difference indicates that this performance change is only marginal.
When Annie tries to synergize with Kha'Zix, she gets a small increase in her total damage dealt. This difference may indicate that Kha'Zix supports by providing protection for her to deal more damage or that his presence on the team also helps increase the round's duration. Similarly, when Annie is played alongside Kha'Zix on the same side, he usually scores many fewer killing sprees compared to when she plays without Kha'Zix. This is contrasting evidence that she is worse when playing synergisticly with Kha'Zix.
Moreover, when Annie plays with Kha'Zix on the same team, she usually receives a little more damage than when she fights alone. Taking more damage could mean that Kha'Zix does a poor job of protecting Annie in team fights.
There is no one best synergy for Annie that will no matter what be her best ally. However, Kha'Zix is a good ally for Annie. By being on the same side as Annie, he raises their win rate by 1.6% to 50.9%. This proves that there is a potentially meaningful synergy between Annie and Kha'Zix that results in them performing at the top of their game together than without each other.
Kha'Zix has a lower difficulty than Annie. That means Annie players don't need to be very careful when lining up Kha'Zix teammates to go into battle on the same side as, as they will have to have a lower level of skill to be able to play well with you.
When playing alongside, Annie players will likely see an overall large increase in your team’s ability to deal magical damage. Combined, these two can deal quite a lot of AP type damage.
Conversely, by bringing Annie and Kha'Zix together, you may not be granting your team very much engage potential. Make sure to include other champions on your team that neutralizes this relative hole in this pairing's abilities.
Regardless of the ability of your Kha'Zix teammate, you should focus on maximizing your income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you will do well, regardless.
If you would like to truly master Annie to pair well with Kha'Zix during both the laning and mid / late game phases of League of Legends games, you should keep reading to pick up some more tips and tricks for this champion pairing. If you mind the build and tips shown here, you will increase your win rate by a lot.
The top items to prioritize in your Annie and Kha'Zix synergy build include Malignance, Shadowflame, and Liandry's Torment. When Annie incorporated at least these three great items in her build, she did much better as an ally of Kha'Zix than with many other typical builds. In fact, Annie boasted an average winrate of 50.9% when playing alongside Kha'Zix with these items in her kit.
To have the greatest likelihood of crushing your oponents, you should take the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Absolute Focus, and Manaflow Band runes from the Domination and Sorcery rune sets. Out of all the runes we have analyed for Annie and Kha'Zix pairings, this combo of runes resulted in the highest win rate. Notably, these runes provided a 50.9% winrate overall.
If you want to view Annie and Kha'Zix collaboration tips and stats for a a specific rank, feel free to select one from the selection menu displayed above. At first, the statistics and tips and suggestions displayed are computed using every match finished with these champions.