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The Seraphine Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Seraphine sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This drop shows that Karthus helps Seraphine perform poorer in competitive League of Legends rounds. Yet, the small difference demonstrates that this performance change is only marginal.
When Seraphine plays on the same team as Karthus, she sees a little drop in her full damage output. This could indicate that Karthus does not provide cover for her to deal more damage or that his presence on the team also helps extend the round's duration. Similarly, when Seraphine is played alongside Karthus on the same side, he usually scores many fewer killing sprees compared to when she plays without Karthus. This is contrasting evidence that she is worse when playing alongside Karthus.
Additionally, when Seraphine plays with Karthus on the same team, she usually receives more damage than when she fights alone. Taking more damage could mean that Karthus does a poor job of protecting Seraphine in teamfights.
There is no one best champion pairing for Seraphine that will 100% of the time be her top ally. However, overall, Karthus is a very bad companion for Seraphine. By locking into the same side as Seraphine, he decreases their win rate by -3.5% to 46.5%. This clearly indicates that there is an easy to overcome and exploit synergy between Seraphine and Karthus that results in them performing worse together than without each other.
Karthus has a much greater difficulty compared to Seraphine. That means Seraphine players need to be cautious when finding Karthus teammates to play with, as they will need a much greater level of skill to be able to work well with you.
When playing on the same side, Seraphine players should see an overall large increase in your team’s capacity to support your allies. Combined, these two should be able to manipulate the pace of team fights.
Although, by grouping Seraphine and Karthus together, you may not be giving your other teammates very much attack damage. Make sure to include other champions on your team that fills this gap in this pairing's playstyle.
Regardless of the skill of your Karthus teammate, you need to focus on increasing your income, outlasting your enemies, and clearing objectives. If you follow these simple suggestions, you should do well anyway.
If you would like to truly master Seraphine to pair well with Karthus during both the laning and mid / late game phases of League games, you should continue reading to master some more lessons on this champion pairing. If you listen to the build and suggestions displayed above, you will grow your win rate by a lot.
The most important items to get in your Seraphine and Karthus synergy build consist of Abraço de Seraph, Cajado Aquafluxo, and Auronúcleo. When Seraphine incorporated at least these three finished items in her build, she did a lot better when fighting alongside Karthus than with many other common builds. In fact, Seraphine had an average winrate of 46.5% when playing alongside Karthus with this build.
To have the best probability of vanquishing your oponents, Seraphine players should equip the Cometa Arcano, Faixa de Fluxo de Mana, Transcendência, Chamuscar, Entrega de Biscoitos, and Perspicácia Cósmica runes from the Feitiçaria and Inspiração rune sets. Out of all the rune builds players chose for this team composition, this combo of runes yielded the best win rate. In fact, these runes gave a 46.5% win rate overall.
By default, tips, statistics, and builds on how to team up Karthus with Seraphine are shown for every ranked division. If you would like to scope the statistics and builds to a specific player tier, you should use the selection menu located above.